Results 81 to 90 of about 361,099 (313)

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Divide-and-Conquer: Frequency-Domain Decoupling Strategy for Low-Light Remote Sensing Image Enhancement

IEEE Journal of Selected Topics in Applied Earth Observations and Remote Sensing
Low-light remote sensing (RS) images typically cover vast areas. They contain objects of various scales and have localized light sources. This makes it challenging to enhance brightness while preserving fine image structures.
Bosong Zhuang, Zishu Yao, Guodong Fan, Jinjiang Li   +3 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

An Application-Oriented Approach for Accelerating Data-Parallel Computation with Graphics Processing Unit

, 2009
This paper presents a novel parallelization and quantitative characterization of various optimization strategies for data-parallel computation on a graphics processing unit (GPU) using NVIDIA's new GPU programming framework, Compute Unified Device ...
Ponce, Sean, Quek, Francis, Cao, Yong, Jing, Huang, Park, Seung In, Khoury, Chase   +5 more
core  

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

DAPNA: an architectural framework for data processing networks [PDF]

, 2013
Due to copyright restrictions, the access to the full text of this article is only available via subscription.A data processing network is as a set of (software) components connected through communication channels to apply a series of operations on data.
Paolo Perona, Nouta, S., Sander Nouta, Nouta, Sander, Perona, P., Hasan Sözer, Sözer, Hasan, Perona, Paolo, Wombacher, A., Andreas Wombacher, Wombacher, Andreas   +10 more
core   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

Investigation into the wafer-scale integration of fine-grain parallel processing computer systems [PDF]

, 1986
This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.This thesis investigates the potential of wafer-scale integration (WSI) for the implementation of low-cost fine-grain parallel processing computer systems ...
Jones, Simon Richard
core  

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

FEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga, Toshiki Takahashi, Akiko Kuma, Hiroyuki Kawahara   +3 more
wiley   +1 more source

Experiential sampling in multimedia systems

, 2006
Multimedia systems must deal with multiple data streams. Each data stream usually contains significant volume of redundant noisy data. In many real-time applications, it is essential to focus the computing resources on a relevant subset of data streams ...
Wang, J, Kankanhalli, M.S., Kankanhalli, MS, Wang, J., Jain, R., Jain, R   +5 more
core   +1 more source