Results 131 to 140 of about 5,645,319 (318)
, 2010 Objective: To investigate how a multilevel item response theory (IRT) model for longitudinal dependent data could provide average and individual quality-of-life outcomes of low-vision rehabilitation.
van Nispen, R.M.A. +5 more
core +1 more source
Regulatory landscape with U.S. patient requirements and Clinical Trial Diversity expectations
Contemporary Clinical Trials CommunicationsThe Food and Drug Administration (FDA) has an expectation that products filed for marketing authorization have to include data that are representative of the US patient population.
Elizabeth George +6 more
doaj +1 more source
The human gut microbiome across the life course
FEBS Letters, EarlyView.Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
wiley +1 more source
FEBS Letters, EarlyView.Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
wiley +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
2006 Texas Index of Water Quality Impairments (June 27, 2007)
, 2007 This report contains a list of the most prominent impairments found in water bodies across Texas, including Waller Creek.Waller Creek Working ...
Texas Commission on Environmental Quality
core +1 more source
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
This dataset contains the following data tables: amss_insitu_participant_data.csv: Participant responses to site evaluation comb_obj_insitu_session_data.csv: Per session combined objective acoustic measurement and subjective response data The ...
Ooi, Kenneth +5 more
core +1 more source
The quality of quality-of-life outcome data: The challenge of data interpretation [PDF]
Resuscitation, 2020 openaire +2 more sources