Results 131 to 140 of about 32,662,171 (307)

A multilevel item response theory model was investigated for longitudinal vision-related quality-of-life data

open access: yes, 2010
Objective: To investigate how a multilevel item response theory (IRT) model for longitudinal dependent data could provide average and individual quality-of-life outcomes of low-vision rehabilitation.
van Nispen, R.M.A.   +5 more
core   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Quality Matters overview

open access: yes, 2016
The presentation provides overview of the Quality Matters services and best practices.We do not provide public access to this presentation.
Quality Matters
core  

Data Policies, Data Management and the Quality of Academic Writing

open access: yes
The quality of methodology sections is the result of interaction between academic cultures of data sharing, effective application of rules, academic excellence and good quality Research Data Management (RDM).This data set is based on the coding of 66 ...
Jensen, Uwe, GESIS - Leibniz Institute for the Social Sciences   +2 more
core   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Oregon DEQ air quality monitoring ... annual report

open access: yes, 1998
Covers OCLC #42360784, OCLC #1024315364, OCLC #12281291921998-Title from cover.Mode of access: Internet from the Oregon Government Publications Collection.This archived document is maintained by the Oregon State Library as part of the Oregon Documents ...

core  

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

Quality Improvement Division Operational Plan 2016 [PDF]

open access: yes, 2016
This is the second Operational Plan for the Quality Improvement Division (QID) since its establishment in 2015 and it builds on the work in 2015 to enable the HSE develop and implement a quality improvement agenda and capability across all levels of the ...
Quality Improvement Division
core  

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