Results 121 to 130 of about 2,154,085 (300)
PERENCANAAN KOLAM RETENSI SEBAGAI UPAYA PENGENDALIAN BANJIR PADA DAERAH ALIRAN SUNGAI WELANG PASURUAN [PDF]
Floods are natural disasters that occur in major cities throughout Indonesia. The causes of floods can be attributed to various factors, including topography, high rainfall intensity, blockage of water channels, and so on.
Mahdiyah, Risyah
core
Land-use effects on soil-water retention characteristic [PDF]
, 2002 Tillage can negatively affect soil physical properties such as bulk density, organic matter content, and soil hydraulic properties, which in turn affect how plants grow. The objective of this study was to evaluate water retention characteristics of a Jay
Brye, Kristofor, Colton, Naomi
core +2 more sources
YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma
Molecular Oncology, EarlyView.The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy +9 more
wiley +1 more source
Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids
Molecular Oncology, EarlyView.This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici +8 more
wiley +1 more source
Molecular Oncology, EarlyView.Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié +16 more
wiley +1 more source
ROASMI: accelerating small molecule identification by repurposing retention data
Journal of CheminformaticsThe limited replicability of retention data hinders its application in untargeted metabolomics for small molecule identification. While retention order models hold promise in addressing this issue, their predictive reliability is limited by uncertain ...
Fang-Yuan Sun +7 more
doaj +1 more source
Nurses' retention and hospital characteristics in New South Wales, CHERE Discussion Paper No 52 [PDF]
Nursing shortages are commonly observed features of hospital systems in Australia, Europe and the United States. To date there has been very little research on the effects of hospital characteristics on the retention of the nursing staff.
Denise Doiron, Glenn Jones
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Molecular Oncology, EarlyView.This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker +16 more
wiley +1 more source
How can integrated working be improved to aid secondary transfer rates for Traveller children? (Sharing our experience, Practitioner-led research 2008-2009; PLR0809/023) [PDF]
, 2009 This research question arose though the lead practitioner’s professional practice, which is focused upon the transfer and retention of Traveller children from primary to secondary school.
D'Arcy, Kate
core
Molecular Oncology, EarlyView.This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad +17 more
wiley +1 more source