Results 101 to 110 of about 13,846,560 (292)
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Graphing of E-Science Data with varying user requirements [PDF]
, 2011 Based on our experience in the Swiss Experiment, exploring experimental, scientific data is often done in a visual way. Starting from a global overview the users are zooming in on interesting events.
Aly, Robin, Wombacher, Andreas
core +2 more sources
CoRR, 2017 Notes for a talk at LEARN Final Conference, Economic Commission for Latin America and the Caribbean (ECLAC), Senate House, University of London, London, May 5th ...
openaire +2 more sources
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
iScienceSummary: This study aimed to develop a methodology to strengthen coordination between ground ambulances and helicopter emergency medical services (EMS) for rapid patient transport.
Soyoung Jung, Xiao Qin, Sooyeon Lim
doaj +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Improving Earth Science Data Literacy [PDF]
The improvement of scientific literacy across the public can take on a myriad of forms and activities. The vast archives of NASAs Earth science data, as one example, reflect the agencys ongoing commitment to producing the highest quality data, services ...
Behnke, Jeanne +2 more
core +1 more source
DataHub: Collaborative Data Science & Dataset Version Management at Scale [PDF]
, 2014 Relational databases have limited support for data collaboration, where teams collaboratively curate and analyze large datasets. Inspired by software version control systems like git, we propose (a) a dataset version control system, giving users the ...
Bhardwaj, Anant +6 more
core +2 more sources