Results 111 to 120 of about 13,846,560 (292)
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Bringing Interdisciplinary Data Science Education Challenges into the Classroom
Journal of Statistics and Data Science EducationThis article examines the growing prevalence and challenges of interdisciplinary data science education (IDSE) in higher education globally. We argue that while data science education has traditionally focused on statistical and computational skills ...
Zofia Bednarowska-Michaiel +1 more
doaj +1 more source
National Space Science Data Center (NSSDC) Data Listing [PDF]
Satellite and nonsatellite data available from the National Space Science Data Center are listed. The Satellite Data listing includes the spacecraft name, launch date, and an alphabetical list of experiments.
core +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
A Systematic Literature Review of Undergraduate Data Science Education Research
Journal of Statistics and Data Science EducationThe presence of data science has been profound in the scientific community in almost every discipline. An important part of the data science education expansion has been at the undergraduate level.
Mine Dogucu +4 more
doaj +1 more source
Shared data science infrastructure for genomics data
BMC Bioinformatics, 2019 Background Creating a scalable computational infrastructure to analyze the wealth of information contained in data repositories is difficult due to significant barriers in organizing, extracting and analyzing relevant data.
Hamid Bagheri +4 more
doaj +1 more source
CoRR, 2020 Phylogenomics is a new field which applies to tools in phylogenetics to genome data. Due to a new technology and increasing amount of data, we face new challenges to analyze them over a space of phylogenetic trees. Because a space of phylogenetic trees with a fixed set of labels on leaves is not Euclidean, we cannot simply apply tools in data science ...
openaire +2 more sources
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source