Results 131 to 140 of about 53,144,553 (313)

Science needs data

open access: yesWirtschaftsdienst, 2020
Regina T. Riphahn
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

National Identity, 2013, Norwegian part of ISSP

open access: yes
This survey is carried out on the basis of the research collaboration in "The International Social Survey Programme" (ISSP). ISSP is an international organisation that prepares and coordinates annual surveys in its member countries, mainly within the ...
Norwegian Sociale Science Data Services
core  

A Social Science Data Fusion Tool and the Data Management through e-Social Science (DAMES) Infrastructure

open access: yes, 2010
The last two decades have seen substantially increased potential for quantitative social science research. This has been made possible by the significant expansion of publicly available social science datasets, the development of new analysis ...
Jones, Simon   +15 more
core   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Environment, 1993, Norwegian part of ISSP

open access: yes
This survey is carried out on the basis of the research collaboration in "The International Social Survey Programme" (ISSP). ISSP is an international organisation that prepares and coordinates annual surveys in its member countries, mainly within the ...
Norwegian Social Science Data Services
core  

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Environment, 2000, Norwegian part of ISSP

open access: yes
This survey is carried out on the basis of the research collaboration in "The International Social Survey Programme" (ISSP). ISSP is an international organisation that prepares and coordinates annual surveys in its member countries, mainly within the ...
Norwegian Social Science Data Services
core  

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

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