Results 161 to 170 of about 13,718,038 (321)

Growing Diversity in Data Science: Shared Lessons from Clinical Trials [PDF]

, 2019
Simari, Robert D.
core   +2 more sources

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

Data Science Altmetrics

Journal of Data and Information Science, 2017
Thelwall Mike
doaj   +1 more source

Heritage data science

, 2022
openaire   +2 more sources

1. Data Science [PDF]

Digitale Welt, 2018
openaire   +1 more source

NOMAD on ExoMars TGO: Data processing and public release via the ESA Planetary Science Archive

, 2020
Ian Thomas, Ann Carine Vandaele, Frank Daerden, Bojan Ristic, Yannick Willame, C. Depiesse, Shohei Aoki, Loïc Trompet, Justin Erwin, Séverine Robert, Arianna Piccialli, Lori Neary, S. Viscardy, Jon Mason, Manish Patel, G. Bellucci, J. J. López‐Moreno   +16 more
openalex   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source

Data science without borders: bridging the divide in data science capacity across African health institutions. [PDF]

Front Public Health
Kiragga AN, Iddi S, Walekhwa AW, Barasa M, Cygu S, Odhiambo R, Gningue M, Mboup A, Onana A, Adnew B, Alemu Ashuro A, Hudson S, Greenfield J, Todd J, Bhattacharjee T, Sharan M, Sonabend R, Kadengye D, Mbatchou BH, Abdissa A, Sarr M, Nabende JN, Bamutura M, Tamurat B, Dereje N, Temfack E.   +25 more
europepmc   +1 more source