Results 71 to 80 of about 13,718,038 (321)
ABSTRACT Objectives To identify predictors of chronic ITP (cITP) and to develop a model based on several machine learning (ML) methods to estimate the individual risk of chronicity at the timepoint of diagnosis. Methods We analyzed a longitudinal cohort of 944 children enrolled in the Intercontinental Cooperative immune thrombocytopenia (ITP) Study ...
Severin Kasser +6 more
wiley +1 more source
Building Data Science Infrastructures and Infrastructural Data Science
Xiao-Li Meng
doaj +1 more source
ABSTRACT Surveillance imaging aims to detect tumour relapse before symptoms develop, but it's unclear whether earlier detection of relapse leads to better outcomes in children and young people (CYP) with medulloblastoma and ependymoma. This systematic review aims to identify relevant literature to determine the efficacy of surveillance magnetic ...
Lucy Shepherd +3 more
wiley +1 more source
ABSTRACT Introduction Neuroblastoma (NB) with central nervous system (CNS) metastases is rare at diagnosis, but occurs more often during relapse/progression. Patients with CNS metastases face a dismal prognosis, with no standardized curative treatment available.
Vicente Santa‐Maria Lopez +13 more
wiley +1 more source
Lessons learned to improve the UX practices in agile projects involving data science and process automation [PDF]
Bruna Ferreira +4 more
openalex +1 more source
Pathogenic Germline PALB2 and RAD50 Variants in Patients With Relapsed Ewing Sarcoma
ABSTRACT Approximately 10% of patients with Ewing sarcoma (EwS) have pathogenic germline variants. Here, we report two cases: first, a novel germline pathogenic variant in partner and localizer of BRCA2 (PALB2) in a patient with a late EwS relapse. Its impact on homologous recombination is demonstrated, and breast cancer risk is discussed.
Molly Mack +12 more
wiley +1 more source
Data science and data analytics in life science research
Jürgen Bajorath
doaj +1 more source
Intersections between Information Science and Big Data
The aim of this work is to identify the interrelationships between Big Data and Information Science based on a literature review of scientific communications indexed in the Scopus and Web of Science databases ...
Joel Perozo-Vasquez +2 more
doaj +1 more source
ABSTRACT Background We describe clinical and biologic characteristics of neuroblastoma in older children, adolescents, and young adults (OCAYA); describe survival outcomes in the post‐immunotherapy era; and identify if there is an age cut‐off that best discriminates outcomes.
Rebecca J. Deyell +14 more
wiley +1 more source
Knowledge-based biomedical Data Science
Computational manipulation of knowledge is an important, and often under-appreciated, aspect of biomedical Data Science. The first Data Science initiative from the US National Institutes of Health was entitled “Big Data to Knowledge (BD2K).” The main ...
Lawrence E. Hunter
doaj +1 more source

