Results 91 to 100 of about 3,643,121 (304)
National-scale 10-m maps of cropland use intensity in China during 2018–2023
The amount of actively cultivated land in China is increasingly threatened by rapid urbanization and rural population aging. Quantifying the extent and changes of active cropland and cropping intensity is crucial to global food security.
Bingwen Qiu +11 more
doaj +1 more source
ICA-ASIFT-Based Multi-Temporal Matching of High-Resolution Remote Sensing Urban Images
While SIFT (Scale Invariant Feature Transform) features are used to match High-Resolution (HR) remote sensing urban images captured at different phases with large scale and view variations, feature points are few and the matching accuracy is low ...
Huang Fenghua, Mao Zhengyuan, Shi Wenzao
doaj +1 more source
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
Assessing spatial information access, use and sharing for catchment management in Australia [PDF]
Spatial data plays an important role in many social, environmental, economic and political decisions and is increasingly acknowledged as a national resource essential for sustainable development.
Apan, Armando +2 more
core
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Publishing and sharing sensitive data [PDF]
Sensitive data has often been excluded from discussions about data publication and sharing. It was believed that sharing sensitive data is not ethical or that it is too difficult to do safely.
Sarah Olesen
core
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Function‐driven design of a surrogate interleukin‐2 receptor ligand
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Building type information indicates the functional properties of buildings and plays a crucial role in smart city development and urban socioeconomic activities.
Shaofeng Zhang +4 more
doaj +1 more source

