Results 91 to 100 of about 23,296,124 (362)

Sharing Is Caring—Data Sharing Initiatives in Healthcare [PDF]

International Journal of Environmental Research and Public Health, 2020
In recent years, more and more health data are being generated. These data come not only from professional health systems, but also from wearable devices. All these ‘big data’ put together can be utilized to optimize treatments for each unique patient (‘precision medicine’). For this to be possible, it is necessary that hospitals, academia and industry
openaire   +4 more sources

Autophagy in cancer and protein conformational disorders

FEBS Letters, EarlyView.
Autophagy plays a crucial role in numerous biological processes, including protein and organelle quality control, development, immunity, and metabolism. Hence, dysregulation or mutations in autophagy‐related genes have been implicated in a wide range of human diseases.
Sergio Attanasio
wiley   +1 more source

National-scale 10-m maps of cropland use intensity in China during 2018–2023

Scientific Data
The amount of actively cultivated land in China is increasingly threatened by rapid urbanization and rural population aging. Quantifying the extent and changes of active cropland and cropping intensity is crucial to global food security.
Bingwen Qiu, Baoli Liu, Zhenghong Tang, Jinwei Dong, Weiming Xu, Juanzhu Liang, Nan Chen, Jiangping Chen, Laigang Wang, Chengming Zhang, Zhengrong Li, Fangzheng Wu   +11 more
doaj   +1 more source

P‐glycoprotein modulates the fluidity gradient of the plasma membrane of multidrug resistant CHO cells

FEBS Letters, EarlyView.
To explore the impact of the overexpression of the multidrug‐transporter P‐glycoprotein (ABCB1) on membrane fluidity, we compared the transversal gradient of mobility and microviscosity in plasma membranes of drug‐sensitive Chinese hamster ovary cells (AuxB1) and their multidrug‐resistant derivatives (B30) using the fluorescent n‐(9‐anthroyloxy) fatty ...
Roger Busche, John R. Riordan, Burkhard Tümmler   +2 more
wiley   +1 more source

A coiled‐coil domain triggers oligomerization of MmpL10, the mycobacterial transporter of trehalose polyphleate precursor

FEBS Letters, EarlyView.
Most MmpLs transport lipids and glycolipids of the complex mycomembrane of mycobacteria. This study shows that MmpL10 from Mycobacterium smegmatis, the transporter of the trehalose polyphosphate precursor, harbors a coiled‐coil‐like extension. Biochemical and electron microscopy studies demonstrate that the coiled‐coil enables MmpL10 to trimerize.
Julie Couston, Jérôme Feuillard, Aurélie Ancelin, Joséphine Lai‐Kee‐Him, Konstantin Brodolin, Christian Chalut, Pontus Gourdon, Mickaël Blaise   +7 more
wiley   +1 more source

Building Type Classification Using CNN-Transformer Cross-Encoder Adaptive Learning From Very High Resolution Satellite Images

IEEE Journal of Selected Topics in Applied Earth Observations and Remote Sensing
Building type information indicates the functional properties of buildings and plays a crucial role in smart city development and urban socioeconomic activities.
Shaofeng Zhang, Mengmeng Li, Wufan Zhao, Xiaoqin Wang, Qunyong Wu   +4 more
doaj   +1 more source

Unlocking the potential of tumor‐derived DNA in urine for cancer detection: methodological challenges and opportunities

Molecular Oncology, EarlyView.
Urine is a rich source of biomarkers for cancer detection. Tumor‐derived material is released into the bloodstream and transported to the urine. Urine can easily be collected from individuals, allowing non‐invasive cancer detection. This review discusses the rationale behind urine‐based cancer detection and its potential for cancer diagnostics ...
Birgit M. M. Wever, Renske D. M. Steenbergen   +1 more
wiley   +1 more source

Delineation of agricultural fields using multi-task BsiNet from high-resolution satellite images

International Journal of Applied Earth Observations and Geoinformation, 2022
This paper presents a new multi-task neural network, called BsiNet, to delineate agricultural fields from high-resolution satellite images. BsiNet is modified from a Psi-Net by structuring three parallel decoders into a single encoder to improve ...
Jiang Long, Mengmeng Li, Xiaoqin Wang, Alfred Stein   +3 more
doaj  

Subpar reporting of pre‐analytical variables in RNA‐focused blood plasma studies

Molecular Oncology, EarlyView.
Pre‐analytical variables strongly influence the analysis of extracellular RNA (cell‐free RNA; exRNA) derived from blood plasma. Their reporting is essential to allow interpretation and replication of results. By evaluating 200 exRNA studies, we pinpoint a lack of reporting pre‐analytical variables associated with blood collection, plasma preparation ...
Céleste Van Der Schueren, Philippe Decruyenaere, Francisco Avila Cobos, Johanna Bult, Jill Deleu, Laudonia Lidia Dipalo, Hetty Hilde Helsmoortel, Eva Hulstaert, Annelien Morlion, Elena Ramos Varas, Kathleen Schoofs, Wim Trypsteen, Eveline Vanden Eynde, Hanne Van Droogenbroeck, Kimberly Verniers, Jo Vandesompele, Anneleen Decock   +16 more
wiley   +1 more source

Spatio-Temporal neighbors adaptive learning with two-point differences for ocean subsurface temperature reconstruction from 1960 to 2022

International Journal of Digital Earth
Long time series and accurate subsurface temperature data in the global ocean are essential for ocean warming and climate change studies. The sparse in situ observations in the pre-Argo era hinder the reconstruction of long-time series observational data
An Wang, Hua Su
doaj   +1 more source