Results 121 to 130 of about 3,643,121 (304)

Multiple imputation for sharing precise geographies in public use data

open access: yes, 2012
When releasing data to the public, data stewards are ethically and often legally obligated to protect the confidentiality of data subjects' identities and sensitive attributes.
Reiter, Jerome P., Wang, Hao
core   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

open access: yesMolecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan   +9 more
wiley   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

open access: yesMolecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts   +8 more
wiley   +1 more source

Developing Shared Ways of Seeing Data: The Perils and Possibilities of Achieving Intercoder Agreement

open access: gold, 2023
Sherice N. Clarke   +5 more
openalex   +1 more source

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

open access: yesMolecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath   +13 more
wiley   +1 more source

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

open access: yesMolecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy   +9 more
wiley   +1 more source

Estimating the mixed layer depth of the global ocean by combining multisource remote sensing and spatiotemporal deep learning

open access: yesInternational Journal of Digital Earth
Estimating the ocean mixed layer depth (MLD) is crucial for studying the atmosphere-ocean interaction and global climate change. Satellite observations can accurately estimate the MLD over large scales, effectively overcoming the limitation of sparse in ...
Hua Su   +4 more
doaj   +1 more source

A linked data-driven & service-oriented architecture for sharing educational resources [PDF]

open access: yes, 2011
The two fundamental aims of managing educational resources are to enable resources to be reusable and interoperable and to enable Web-scale sharing of resources across learning communities.
Dietze, Stefan   +8 more
core  

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