Results 111 to 120 of about 26,647,086 (304)

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim   +17 more
wiley   +1 more source

Knowledge concept recognition in the learning brain via fMRI classification

open access: yesFrontiers in Neuroscience
Knowledge concept recognition (KCR) aims to identify the concepts learned in the brain, which has been a longstanding area of interest for learning science and education.
Wenxin Zhang   +7 more
doaj   +1 more source

Optimization of seminal extracellular vesicle isolation protocols for cancer biomarker analysis using proteomic profiling

open access: yesMolecular Oncology, EarlyView.
This paper shows that size‐exclusion chromatography and sequential centrifugation applied to seminal plasma enrich for different populations of extracellular vesicles. This may significantly affect the detection and analysis of extracellular vesicle‐associated cancer biomarkers.
Elen Telumyan   +8 more
wiley   +1 more source

Storage network enhancement

open access: yes, 2012
The volume of data that storage centers are handling is rising exponentially. This is due to increasing dependency by IT executives, trying to avoid rising infrastructural costs, subscribing to the services of technologies such as data storage centers.
Lim, Seth Yew Siong.
core  

Tumour‐proximal deep serum proteomics identifies biomarkers associated with ovarian cancer

open access: yesMolecular Oncology, EarlyView.
New biomarkers are needed for early ovarian cancer detection. Ovarian (tumour‐proximal) and peripheral vein serum from healthy women and patients with benign or malignant tumours underwent nanoparticle‐enriched deep proteomics. Ovarian serum yielded more protein identifications and revealed tumour‐reflective signatures.
Darren Lau   +9 more
wiley   +1 more source

A sequence-based machine learning model for predicting antigenic distance for H3N2 influenza virus

open access: yesFrontiers in Microbiology
IntroductionSeasonal influenza A H3N2 viruses are constantly changing, reducing the effectiveness of existing vaccines. As a result, the World Health Organization (WHO) needs to frequently update the vaccine strains to match the antigenicity of emerged ...
Xingyi Li   +6 more
doaj   +1 more source

Is Storage at a Loss Merely an Illusion of Spatial Aggregation? [PDF]

open access: yes
The storage-at-a-loss paradox—stocks despite inadequate price growth to cover storage costs—is an unresolved issue of long-standing interest to economists.
Franken, Jason R.V.   +2 more
core  

The impact of leukocyte‐associated RNA retention on platelet RNA‐based cancer detection

open access: yesMolecular Oncology, EarlyView.
Platelets carry RNA signals that may help detect cancer, but platelet samples can also retain RNA from white blood cells. We found that this retained white blood cell signal did not significantly affect machine learning cancer classification, suggesting that the cancer‐related RNA signal in platelets is largely independent of leukocyte‐associated RNA ...
Michał Sieczczyński   +12 more
wiley   +1 more source

Enhancing cell subpopulation discovery in cancer by integrating single-cell transcriptome and expressed variants

open access: yesFundamental Research
The emergence of single-cell RNA sequencing (scRNA-seq) technology has revolutionized the study of cellular heterogeneity at the single-cell level. However, existing methods for identifying subpopulations of cells in scRNA-seq data mainly rely on gene ...
Tao Wang   +7 more
doaj   +1 more source

Data for: Distribution System Operation with Energy Storage and Renewable Generation Uncertainty

open access: yes, 2019
Accompaning data for the book chapter: Distribution System Operation with Energy Storage and Renewable Generation ...
Gonzalez-Castellanos, A (via Mendeley Data)   +1 more
core   +1 more source

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