Results 101 to 110 of about 26,647,086 (304)

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

open access: yesMolecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi   +6 more
wiley   +1 more source

Storage aware data management system for Genomics [PDF]

open access: yes
In recent years, nucleotide sequencing has become increasingly instrumental in both research and clinical settings. This has led to explosive growth in sequencing data produced worldwide along with an increase in complex analysis algorithms.
Farid, M., Shah, Z.
core   +1 more source

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

open access: yesMolecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad   +2 more
wiley   +1 more source

An Intelligent Retrieval Method for Audio and Video Content: Deep Learning Technology Based on Artificial Intelligence

open access: yesIEEE Access
To address the challenges of efficient intelligent retrieval and cross-modal analysis brought by the surge in audio-video data, this study proposes an intelligent retrieval method for audio-video content based on deep learning techniques, aimed at ...
Maojin Sun
doaj   +1 more source

Design and Micromagnetic Simulation of Fe/L10-FePt/Fe Trilayer for Exchange Coupled Composite Bit Patterned Media at Ultrahigh Areal Density

open access: yesAdvances in Materials Science and Engineering, 2015
Exchange coupled composite bit patterned media (ECC-BPM) are one candidate to solve the trilemma issues, overcome superparamagnetic limitations, and obtain ultrahigh areal density.
Warunee Tipcharoen   +2 more
doaj   +1 more source

Extracellular vesicle lipidomics liquid biopsy reveals systemic and tumor microenvironment metabolic reprogramming in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani   +9 more
wiley   +1 more source

Data for: Compatibility of vegetable oils with solid filler materials for thermocline thermal energy storage systems.

open access: yes, 2019
Detailed data about compatibility of vegetables oils with solid filler materials devoted to energy storage ...
Goetz, V (via Mendeley Data)   +1 more
core   +1 more source

A role for eIF5A in translational control of stress‐inducible proteins in multiple myeloma cell lines

open access: yesMolecular Oncology, EarlyView.
Loss of eIF5A rewires thapsigargin‐mediated endoplasmic reticulum stress responses in multiple myeloma cells by selective translation of mRNA transcripts, consequently dampening thapsigargin‐induced unfolded protein response (UPR) activation and shifting the balance from induction of apoptosis toward cell survival and proliferation.
Demi Both   +7 more
wiley   +1 more source

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso   +5 more
wiley   +1 more source

Cloud Storage in a private cloud deployment: Lessons for Data Intensive research (Best student paper)

open access: yes, 2012
. This paper demonstrates portability for a private cloud deployment, which has a detailed case study about Cloud Storage service developed as part of the Cloud Computing Business Framework (CCBF).
Walters, Robert John   +8 more
core  

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