Results 81 to 90 of about 25,618,778 (303)

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

FEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux, Christian Lévêque, Fodil Azzaz, Marion Sangiardi, Sarosh R Irani, Michael Seagar, Jacques Fantini, Oussama El Far   +7 more
wiley   +1 more source

Traditional and emerging materials for optical metasurfaces

Nanophotonics, 2017
One of the most promising and vibrant research areas in nanotechnology has been the field of metasurfaces. These are two dimensional representations of metaatoms, or artificial interfaces designed to possess specialized electromagnetic properties which ...
Zhu Alexander Y., Kuznetsov Arseniy I., Luk’yanchuk Boris, Engheta Nader, Genevet Patrice   +4 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

A generic storage API [PDF]

, 2011
Submitted to ACSC 2004 This work was supported by EPSRC grant GR/R45154 "Bulk Storage of XML Documents"We present a generic API suitable for provision of highly generic storage facilities that can be tailored to produce various individually customised ...
Dearle, Alan, Kirby, Graham, Zirintsis, Evangelos, Morrison, Ron   +3 more
core   +2 more sources

Manipulating transient SOT-MRAM switching dynamics for efficiency improvement and probabilistic switching

Scientific Reports
In this paper, we investigate the effect of transient dynamics in the switching process for spin-orbit torque magnetic random-access memory (SOT-MRAM) devices stabilized by in-plane uniaxial magnetocrystalline anisotropy.
Shreyes Nallan, Jian-Gang Zhu
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Cloud Data Storage Services Considering Public Audit for Security [PDF]

, 2013
The cloud computing is a computing technology that allows us to share the pool of configurable sources where the data of individuals or the organisations can be stored remotely those can be accessible on-demand high quality applications.
Swathi Sambangi
core  

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Bandwidth Prediction Based Resource Allocation Scheme for Low-Latency and Energy-Efficient PONs With Heterogeneous ONU Propagation Delays

IEEE Photonics Journal
To achieve low-latency and energy-efficient in a 10 Gbps Ethernet Passive Optical Network (10G-EPON) having heterogeneous Optical Network Unit (ONU) propagation delays, this article proposes a resource allocation scheme based on bandwidth requirements ...
Pengcheng Li, Yunxin Lv, Meihua Bi
doaj   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source