Results 171 to 180 of about 3,654,984 (308)
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
Fast and accurate short-read alignment with hybrid hash-tree data structure. [PDF]
Genomics InformMakino J +3 more
europepmc +1 more source
Harnessing Collective Structure Knowledge in Data Augmentation for Graph Neural Networks
, 2023 Rongrong Ma, Guansong Pang, Ling Chen
openalex +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
The backpack quotient filter: A dynamic and space-efficient data structure for querying k-mers with abundance. [PDF]
iScienceLevallois V +4 more
europepmc +1 more source
Molecular Oncology, EarlyView.We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
Physical and data structure of 3D genome. [PDF]
Sci Adv, 2020 Huang K +9 more
europepmc +1 more source