Results 111 to 120 of about 6,963,647 (337)
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
There is an increasing need for building models that permit interior navigation, e.g., for escape route analysis. This paper presents a non-manifold Computer-Aided Design (CAD) data structure, the dual half-edge based on the Poincaré duality that ...
Pawel Boguslawski, Christopher Gold
doaj +1 more source
fimpera: drastic improvement of Approximate Membership Query data-structures with counts. [PDF]
Robidou L, Peterlongo P.
europepmc +1 more source
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley +1 more source
Dynamic Data Structures for Timed Automata Acceptance. [PDF]
Grez A +4 more
europepmc +1 more source
Time after time – circadian clocks through the lens of oscillator theory
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
Integrating Structured and Unstructured EHR Data for Predicting Mortality by Machine Learning and Latent Dirichlet Allocation Method [PDF]
Chih‐Chou Chiu +5 more
openalex +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Computational graph pangenomics: a tutorial on data structures and their applications. [PDF]
Baaijens JA +6 more
europepmc +1 more source
Prediction of transcript structure and concentration using RNA-Seq data [PDF]
Harsh Sharma +4 more
openalex +1 more source

