Results 81 to 90 of about 37,551,526 (314)
Nucleic Acids Res., 2018 The Research Collaboratory for Structural Bioinformatics Protein Data Bank (RCSB PDB, rcsb.org), the US data center for the global PDB archive, serves thousands of Data Depositors in the Americas and Oceania and makes 3D macromolecular structure data ...
S. Burley +39 more
semanticscholar +1 more source
Single‐cell insights into the role of T cells in B‐cell malignancies
FEBS Letters, EarlyView.Single‐cell technologies have transformed our understanding of T cell–tumor cell interactions in B‐cell malignancies, revealing new T‐cell subsets, functional states, and immune evasion mechanisms. This Review synthesizes these findings, highlighting the roles of T cells in pathogenesis, progression, and therapy response, and underscoring their ...
Laura Llaó‐Cid
wiley +1 more source
network: A Package for Managing Relational Data in R
Journal of Statistical Software, 2007 Effective memory structures for relational data within R must be capable of representing a wide range of data while keeping overhead to a minimum. The network package provides an class which may be used for encoding complex relational structures composed
Carter T. Butts
doaj
Parallel construction of binary tree based on sorting
Advanced Engineering Research, 2018 Introduction. Algorithms for the parallel binary tree construction are developed. The algorithms are based on sorting and described in a constructive form. For the Nelement set, the time complexity has T(R) = O(1) and T(R) = O(log2 N) estimates, where R =
Ya. E. Romm, D. A. Chabanyuk
doaj +1 more source
FEBS Letters, EarlyView.In the adult T‐cell leukemia/lymphoma (ATL) cell line ED, the human T‐cell leukemia virus type 1 (HTLV‐1) provirus was integrated into the intron of the ift81 gene in the antisense orientation. Despite this integration, both the intact ift81 and the viral oncogene hbz were simultaneously expressed, likely due to the functional insufficiency of viral ...
Mayuko Yagi +5 more
wiley +1 more source
Cyclic nucleotide signaling as a drug target in retinitis pigmentosa
FEBS Letters, EarlyView.Disruptions in cGMP and cAMP signaling can contribute to retinal dysfunction and photoreceptor loss in retinitis pigmentosa. This perspective examines the mechanisms and evaluates emerging evidence on targeting these pathways as a potential therapeutic strategy to slow or prevent retinal degeneration.
Katri Vainionpää +2 more
wiley +1 more source
Kernel methods for detecting coherent structures in dynamical data
, 2019 We illustrate relationships between classical kernel-based dimensionality reduction techniques and eigendecompositions of empirical estimates of reproducing kernel Hilbert space (RKHS) operators associated with dynamical systems.
Husic, Brooke E. +3 more
core +1 more source
TRAF2 binds to TIFA via a novel motif and contributes to its autophagic degradation
FEBS Letters, EarlyView.TRAF family members couple receptor signalling complexes to downstream outputs, but how they interact with these complexes is not always clear. Here, we show that during ADP‐heptose signalling, TRAF2 binding to TIFA requires two short sequence motifs in the C‐terminal tail of TIFA, which are distinct from the TRAF6 binding motif.
Tom Snelling +4 more
wiley +1 more source
Exploring multivariate data structures with local principal curves. [PDF]
, 2005 A new approach to find the underlying structure of a multidimensional data cloud is proposed, which is based on a localized version of principal components analysis. More specifically, we calculate a series of local centers of mass and move through the
Einbeck, Jochen +4 more
core +1 more source
Predicting Crystal Structures with Data Mining of Quantum Calculations
, 2003 Predicting and characterizing the crystal structure of materials is a key problem in materials research and development. It is typically addressed with highly accurate quantum mechanical computations on a small set of candidate structures, or with ...
A. Zunger +19 more
core +1 more source