Results 91 to 100 of about 1,559,860 (292)

Data intensive applications verification

open access: yes, 2017
The main challenges for a Data-Intensive Application are the data quantity, the data complexity and the speed at which the data changes. For these applications, there are two predominant data categories, Master Data and Transactional Data. Master Data represents the data that is not frequently modified and that is required for the system to operate ...
openaire   +2 more sources

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

International database of reference gamma spectra for nuclear safeguards applications

open access: yesScientific Data
Nuclear safeguards missions use gamma spectroscopy as a non-destructive measurement technique for examining nuclear materials. Despite advances in the development of detection equipment as well as software codes, one of the concerns is the lack of well ...
Dipti   +9 more
doaj   +1 more source

Verité Update, vol. 3: Child Labor in Chocolate Industry [PDF]

open access: yes, 2009
This issue of Verite Update announces Verite’s new independent verification process, the Road Map, which brings NGOs, governments, and industry together to establish a common platform through which to gather data that accurately reflects conditions on ...
Verité
core   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

Group Membership Prediction

open access: yes, 2015
The group membership prediction (GMP) problem involves predicting whether or not a collection of instances share a certain semantic property. For instance, in kinship verification given a collection of images, the goal is to predict whether or not they ...
Chen, Yuting   +2 more
core   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Quantifying verification uncertainty by reference data variation

open access: yesMeteorologische Zeitschrift, 2012
In the framework of a multi-level verification experiment, the impact of different characteristics of verification reference data on NWP-model verification is evaluated.
Theresa Gorgas, Manfred Dorninger
doaj   +1 more source

Thermal Pollution Mathematical Model. Volume 4: Verification of Three-Dimensional Rigid-Lid Model at Lake Keowee [PDF]

open access: yes
The rigid lid model was developed to predict three dimensional temperature and velocity distributions in lakes. This model was verified at various sites (Lake Belews, Biscayne Bay, etc.) and th verification at Lake Keowee was the last of these series of ...
Lee, S. S.   +3 more
core   +1 more source

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