Results 41 to 50 of about 1,372,066 (309)

Brucella NyxA and NyxB dimerization enhances effector function during infection

FEBS Letters, EarlyView.
Brucella abortus thrives inside cells thanks to the translocation of effector proteins that fine‐tune cellular functions. NyxA and NyxB are two effectors that destabilize the nucleolar localization of their host target, SENP3. We show that the Nyx proteins directly interact with each other and that their dimerization is essential for their function ...
Lison Cancade‐Veyre, Arthur Louche, Francine C. A. Gérard, Laurent Terradot, Suzana P. Salcedo   +4 more
wiley   +1 more source

Pixel-wise segmentation of cells in digitized Pap smear images

Scientific Data
A simple and cheap way to recognize cervical cancer is using light microscopic analysis of Pap smear images. Training artificial intelligence-based systems becomes possible in this domain, e.g., to follow the European recommendation to screen negative ...
Balazs Harangi, Gergo Bogacsovics, Janos Toth, Ilona Kovacs, Erzsebet Dani, Andras Hajdu   +5 more
doaj   +1 more source

The State of the Art in Empirical User Evaluation of Graph Visualizations

IEEE Access, 2021
While graph drawing focuses more on the aesthetic representation of node-link diagrams, graph visualization takes into account other visual metaphors making them useful for graph exploration tasks in information visualization and visual analytics ...
Michael Burch, Weidong Huang, Mathew Wakefield, Helen C. Purchase, Daniel Weiskopf, Jie Hua   +5 more
doaj   +1 more source

Multidimensional data visualization [PDF]

Behavior Research Methods, Instruments, & Computers, 2002
Historically, data visualization has been limited primarily to two dimensions (e.g., histograms or scatter plots). Available software packages (e.g., Data Desk 6.1, MatLab 6.1, SAS-JMP 4.04, SPSS 10.0) are capable of producing three-dimensional scatter plots with (varying degrees of) user interactivity.
Matthew J. Pastizzo, Robert F. Erbacher, Laurie Beth Feldman   +2 more
openaire   +3 more sources

The carboxylate “gripper” of the substrate is critical for C‐4 stereo‐inversion by UDP‐glucuronic acid 4‐epimerase

FEBS Letters, EarlyView.
UDP‐glucuronic acid 4‐epimerase (UGAepi) catalyzes NAD+‐dependent interconversion of UDP‐glucuronic acid (UDP‐GlcA) and UDP‐galacturonic acid (UDP‐GalA) via C4‐oxidation, 4‐keto‐intermediate rotation, and C4‐reduction. Here, Borg et al. examined the role of the substrate's carboxylate group in the enzymic mechanism by analyzing NADH‐dependent reduction
Annika J. E. Borg, Laura De Cnop, Bernd Nidetzky   +2 more
wiley   +1 more source

Contribution of Artificial Intelligence (AI) to Code-Based 3D Modeling Tasks

Designs
The rapid advancement of technology and innovation is also impacting education across different levels. The rise of Artificial Intelligence (AI) is beginning to transform education in various areas, from course materials to assessment systems.
Marianna Zichar, Ildikó Papp
doaj   +1 more source

In vivo evidence for glycyl radical insertion into a catalytically inactive variant of pyruvate formate‐lyase

FEBS Letters, EarlyView.
Dimeric pyruvate formate‐lyase cleaves pyruvate using a radical‐based mechanism. G734 serves as a radical storage location, and the radical is transferred to the catalytic C419 residue. Mutation of the C418‐C419 pair causes loss of enzyme activity, but does not impede radical introduction onto G734. Therefore, cis‐ but not trans‐radical transfer occurs
Michelle Kammel, A. F. Volker Wagner, R. Gary Sawers   +2 more
wiley   +1 more source

Stochastic Fusion Techniques for State Estimation

Computation
The fusion process considers the boundary between correct and conflict records. It has been a fundamental component in ensuring the accuracy of many mathematical algorithms that utilize multiple input sources.
Alaa H. Ahmed, Henrietta Tomán
doaj   +1 more source

Data Visualization in Society [PDF]

, 2020
Today we are witnessing an increased use of data visualization in society. Across domains such as work, education and the news, various forms of graphs, charts and maps are used to explain, convince and tell stories. In an era in which more and more data are produced and circulated digitally, and digital tools make visualization production increasingly
Martin Engebretsen, Helen Kennedy, Jill Walker, Giorgia Aiello, Torgeir Uberg, Eef Masson, Karin van, Salla-Maaria Laaksonen, Juho Pääkkönen, Mikael Snaprud, Andrea Velazquez, Arran L., Christopher Birchall, Daniela Geenen, Maranke Wieringa, Jill Simpson, Wibke Weber, Elise Seip Tønnessen, Catherine D’Ignazio, Rahul Bhargava, Lulu Pinney, Arlene Archer, Travis Noakes, Sara Brinch, Tuomo Hiippala, Jonathan Gray, Verena Elisabeth Lechner, Aria Alamalhodaei, Alexandra Alberda, Anna Feigenbaum, John P. Wihbey, Sarah J. Jackson, Pedro M. Cruz, Brooke Foucault Welles, Rosemary Lucy Hill, Britta Ricker, Menno-Jan Kraak, Yuri Engelhardt, Anna Berti Suman, Miren Gutiérrez, Alberto Cairo   +40 more
openaire   +5 more sources

P‐glycoprotein modulates the fluidity gradient of the plasma membrane of multidrug resistant CHO cells

FEBS Letters, EarlyView.
To explore the impact of the overexpression of the multidrug‐transporter P‐glycoprotein (ABCB1) on membrane fluidity, we compared the transversal gradient of mobility and microviscosity in plasma membranes of drug‐sensitive Chinese hamster ovary cells (AuxB1) and their multidrug‐resistant derivatives (B30) using the fluorescent n‐(9‐anthroyloxy) fatty ...
Roger Busche, John R. Riordan, Burkhard Tümmler   +2 more
wiley   +1 more source