Results 101 to 110 of about 2,604,170 (298)
Database and Modern Database Technology
This paper articulates a holistic approach to study the future of database development as well as the interaction between AI and modern database technologies. Overall architecture is data-centric so that quality of data, security, and governance are enhanced. It addresses the scalability and cost-effectiveness of cloud-native versus serverless database
null Mr. Godly C Mathew Zachariah +4 more
openaire +1 more source
Freely available mean daily discharge series from Czechia: what can be inferred from them?
Most hydrometeorological data from Czechia are still provided for a fee. This especially applies to time series with a finer step than monthly. The fact that the data must be paid with respect to an expert’s appraisement and that the proper licence ...
Ledvinka Ondrej
doaj +1 more source
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola +12 more
wiley +1 more source
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
WebCSD: the online portal to the Cambridge Structural Database [PDF]
Ian Thomas +5 more
openalex +1 more source
Protein O‐glycosylation in the Bacteroidota phylum
Species of the Bacteroidota phylum exhibit a unique O‐glycosylation system. It modifies noncytoplasmic proteins on a specific amino acid motif with a shared glycan core but a species‐specific outer glycan. A locus of multiple glycosyltransferases responsible for the synthesis of the outer glycan has been identified.
Lonneke Hoffmanns +2 more
wiley +1 more source
Under environmental changes, the expression level of neuropeptide (NP) and neuropeptide receptor (NPR) genes changes to confer context‐dependent adaptation to the model organism Drosophila melanogaster. Through finding more regulatory elements in the NPR genes in comparison with their ligands (NPs), we found that NPR‐biased transcriptional regulation ...
SeungHeui Ryu +6 more
wiley +1 more source
A global database and “state of the field” review of research into ecosystem engineering by land animals [PDF]
Nicole Coggan +2 more
openalex +1 more source
The EPiC database: Hybrid embodied environmental flow coefficients for construction materials
Robert H. Crawford +2 more
openalex +2 more sources
Spatial selection of sparse pivots for similarity search in metric spaces
Similarity search is a fundamental operation for applications that deal with unstructured data sources. In this paper we propose a new pivot-based method for similarity search, called Sparse Spatial Selection (SSS). The main characteristic of this method
Nieves Rodríguez Brisaboa +3 more
doaj

