Results 61 to 70 of about 2,545,510 (297)
TogoVar: A comprehensive Japanese genetic variation database
Human Genome Variation, 2022 Genomic database: Genetic variation patterns in Japan A comprehensive database of genome sequence differences found in Japanese individuals is helping researchers uncover the genetic basis of diseases occurring in the Japanese population.
Nobutaka Mitsuhashi +6 more
doaj +1 more source
TRY—A plant trait database of databases [PDF]
Global Change Biology, 2019 Plant traits, such as height or specific leaf area, are expressions of plant performance and are important indicators of ecosystem function. Here, the TRY plant database is highlighted as the most comprehensive archive of global plant data, with open access to the public.
openaire +3 more sources
Cancer cell death induced by the NAD antimetabolite Vacor discloses the antitumor potential of SARM1
FEBS Letters, EarlyView.Vacor, a compound converted into the toxic metabolite Vacor adenine dinucleotide (VAD) by the nicotinamide salvage pathway enzymes NAMPT and NMNAT2, exhibits antitumor activity by inducing rapid and complete NAD depletion. We report that Vacor toxicity is limited to cell lines expressing high levels of SARM1, a NAD glycohydrolase.
Giuseppe Ranieri +5 more
wiley +1 more source
BMC Medical Informatics and Decision MakingBackground Virtual Gene Panels (VGP) comprising disease-associated causal genes are utilized in the diagnosis of rare genetic diseases to evaluate candidate genes identified by whole-genome and whole-exome sequencing.
Jaemoon Shin +3 more
doaj +1 more source
HydrobiologyLarge rivers are difficult to sample due to their size yet critical to monitor because humans heavily rely upon and alter them. Aquatic invertebrates are commonly used to assess the ecosystem quality of streams, but methods to sample large rivers are ...
Lusha M. Tronstad, Bryan P. Tronstad
doaj +1 more source
Image databases are not databases with images [PDF]
, 1997 In this paper, we discuss a number of new problems that arise in image databases, and that set them apart from traditional databases. The fact that image databases are based on similarity, rather than matching, creates a whose set of new issues.Most noticeably, while matching is, by and large, a well defined concept, there are many possible types of ...
Ramesh Jain, Simone Santini
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RAD50 missense variants differentially affect the DNA damage response and mitotic progression
FEBS Letters, EarlyView.RAD50 incorporates into the MRN complex and initiates the DNA damage response. Furthermore, RAD50 promotes mitotic progression. RAD50 missense variants capable of forming an MRN complex supported the DNA damage response and mitotic features to different extents in complementation experiments, indicating these functions are separable and might impact ...
Hanna Redeker +9 more
wiley +1 more source
Examining HPO by organ and system to facilitate practical use by clinicians
Genomics & InformaticsThe Human Phenotype Ontology (HPO) is widely used for annotating clinical text data, and sufficient annotation is crucial for the effective utilization of clinical texts.
Eisuke Dohi +4 more
doaj +1 more source
Advances in Laboratory Medicine, 2020 A lo largo de los años se han publicado numerosos artículos sobre variación biológica (VB) de diferente calidad. Los objetivos de este trabajo fueron realizar una revisión sistemática y una evaluación crítica de los estudios de VB para albúmina ...
Ricós Carmen +15 more
doaj +1 more source
Database Slicing on Relational Databases
Acta Cybernetica, 2014 Many software systems today use databases to permanently store their data. Testing, bug finding and migration are complex problems in the case of databases that contain many records. Here, our method can speed up these processes if we can select a smaller piece of the database (called a slice) that contains all of the records belonging to the slicing ...
David Tengeri, Ferenc Havasi
openaire +2 more sources