Results 61 to 70 of about 2,641,789 (298)
BMC Medical Informatics and Decision MakingBackground Virtual Gene Panels (VGP) comprising disease-associated causal genes are utilized in the diagnosis of rare genetic diseases to evaluate candidate genes identified by whole-genome and whole-exome sequencing.
Jaemoon Shin +3 more
doaj +1 more source
HydrobiologyLarge rivers are difficult to sample due to their size yet critical to monitor because humans heavily rely upon and alter them. Aquatic invertebrates are commonly used to assess the ecosystem quality of streams, but methods to sample large rivers are ...
Lusha M. Tronstad, Bryan P. Tronstad
doaj +1 more source
Advances in Laboratory Medicine, 2020 A lo largo de los años se han publicado numerosos artículos sobre variación biológica (VB) de diferente calidad. Los objetivos de este trabajo fueron realizar una revisión sistemática y una evaluación crítica de los estudios de VB para albúmina ...
Ricós Carmen +15 more
doaj +1 more source
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
Crystals, 2019 Interfaces in heterostructures of crystalline materials could strongly affect the slip of dislocations. Such interfaces have become one of the most popular methods to tailor material strength and ductility.
Zhibo Zhang +5 more
doaj +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
POTRET KONFLIK AGRARIA DI INDONESIA
BHUMI: Jurnal Agraria dan Pertanahan, 2018 For the last three years (2010-2013) the conflicts on natural and agrarian resources has taken public attention beginning from the Government, Parliement, National Commission on Human Right to Non Governmental Organization as they frequently took place.
Widiyanto Widiyanto
doaj +1 more source
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
, 2010 Inductive databases are usually viewed as databases that contain models, next to data, such that mining the data essentially boils down to querying them for models. This unifies data mining with database querying. In his chapter, we consider experiment databases.
Vanschoren, Joaquin, Blockeel, Hendrik
openaire +1 more source
Molecular Oncology, EarlyView.This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan +9 more
wiley +1 more source