Results 91 to 100 of about 3,292,616 (334)

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

open access: yesMolecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

Design sensitivity analysis using EAL. Part 1: Conventional design parameters [PDF]

open access: yes
A numerical implementation of design sensitivity analysis of builtup structures is presented, using the versatility and convenience of an existing finite element structural analysis code and its database management system. The finite element code used in
Choi, Kyung K., Dopker, B., Lee, J.
core   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns   +10 more
wiley   +1 more source

دراسة في استخدام اسلوب قاعدة المعلومات في تصميم نظام اجازات المركبات

open access: yesIraqi Journal for Computers and Informatics, 1980
الغرض تطوير العمل في مديرية المرور العامة / مكتب التسجيل ، قام المركز القومي للاستشارات والتطوير الاداري بأجراء دراسة النظامي اجازات السوق والمركبات وقدم تقريرا بذلك في مارس 1976 تضمن عدد من البدائل والتوصيات لتطوير العمل اليدوي لكلا النظامين إلا أن هذه ...
هند فتح الله قندلا
doaj   +1 more source

An integrated database with system optimization and design features [PDF]

open access: yes
A customized, mission-specific relational database package was developed to allow researchers working on the Mars oxygen manufacturing plant to enter physical description, engineering, and connectivity data through a uniform, graphical interface and to ...
Arabyan, A.   +2 more
core   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

open access: yesMolecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel   +6 more
wiley   +1 more source

USE OF DATABASE FORPROJECTION OF DIRECT CURRENT ENGINESFOR MECHANISM DRIVING [PDF]

open access: yesAnalele Universităţii "Constantin Brâncuşi" din Târgu Jiu: Seria Inginerie, 2018
The project of a knowledge databaseof anexpert system is difficultentailing a close collaborationof human expert with theknowledge engineer. The result of such collaborationdeterminesthe accuracy of solutions obtainedby the expert system.
Anca-Olimpia Mosneaga (Talaat-Hamid)   +1 more
doaj  

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

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