Results 191 to 200 of about 15,215,863 (336)

Dynamic Database Management in Computer Aided Residential District Design System [PDF]

, 1998
Jingwen Gu, Huimin Xie
openalex   +1 more source

Teaching Database Design with Constraint-Based Tutors

International Journal of Artificial Intelligence in Education, 2016
A. Mitrovic, P. Suraweera
semanticscholar   +1 more source

Hydrophobicity causes anomalous migration of cystine/glutamate antiporter SLC7A11 in SDS‐PAGE with low acrylamide concentration

FEBS Open Bio, EarlyView.
SLC7A11 frequently migrates faster in SDS‐PAGE. The present study found that the high hydrophobicity of SLC7A11 causes its anomalous migration in SDS‐PAGE with a low concentration of acrylamide gel. Replacing isoleucine with asparagine reduced hydrophobicity and restored its normal migration at 55 kDa, revealing the role of hydrophobicity and gel ...
Nsengiyumva Emmanuel, Qian He, Yixin Kang, Dianbao Zhang, Min Gao, Minglin Wang, Kexin Fan, Jingwen Xiong, Shaobo Wu, Botao Fa, Zhengtao Xiao, Yingfang Niu, Jun Yao, Yilei Zhang   +13 more
wiley   +1 more source

METTL3 knockout accelerates hepatocarcinogenesis via inhibiting endoplasmic reticulum stress response

FEBS Open Bio, EarlyView.
Liver‐specific knockout of N6‐methyladenosine (m6A) methyltransferase METTL3 significantly accelerated hepatic tumor initiation under various oncogenic challenges, contrary to the previously reported oncogenic role of METTL3 in liver cancer cell lines or xenograft models. Mechanistically, METTL3 deficiency reduced m6A deposition on Manf transcripts and
Bo Cui, Silin Tu, Haibo Li, Zhancheng Zeng, Ruiqi Xiao, Jing Guo, Xiaoqi Liang, Chang Liu, Lijie Pan, Wenjie Chen, Mian Ge, Xiaofen Zhong, Linsen Ye, Huaxin Chen, Qi Zhang, Yan Xu   +15 more
wiley   +1 more source

On subcellular distribution of the zinc finger 469 protein (ZNF469) and observed discrepancy in the localization of endogenous and overexpressed ZNF469

FEBS Open Bio, EarlyView.
ZNF469 regulates the expression of genes encoding extracellular matrix proteins. Endogenous ZNF469 is predominantly cytoplasmic, while in transfected cells, it forms aggregates reminiscent of biomolecular condensates, located mainly in the nucleus. These condensates exhibit overlapping staining with proteasomes and are also associated with the mitotic ...
Anne Elisabeth Christensen Mellgren, Ileana Cristea, Thomas Stevenson, Endy Spriet, Per Morten Knappskog, Stig Ove Bøe, Harald Kranz, Sushma N. Grellscheid, Eyvind Rødahl   +8 more
wiley   +1 more source

A new generation of the United States National Land Cover Database: Requirements, research priorities, design, and implementation strategies

Isprs Journal of Photogrammetry and Remote Sensing, 2018
Limin Yang, Suming Jin, P. Danielson, C. Homer, L. Gass, S. Bender, Adam Case, Catherine Costello, J. Dewitz, J. Fry, Michelle Funk, B. Granneman, G. Liknes, M. Rigge, G. Xian   +14 more
semanticscholar   +1 more source

Understanding and Overcoming Immunotherapy Resistance in Skin Cancer: Mechanisms and Strategies

Aging and Cancer, EarlyView.
This narrative review explores the mechanisms driving immunotherapy resistance in skin cancer, including tumor microenvironment factors, genetic mutations, and immune evasion strategies. It highlights potential strategies to overcome resistance, offering insights for improving therapeutic outcomes and guiding future research in personalized ...
Shreya Singh Beniwal, Abhimanyu Chiraparambil Radhakrishnan, Ayanchetty Haripraba, Saif Syed, Gajawada Pragna, Ayush Dwivedi, Akash Rawat, Daniela Castro Calderón, Martin Cevallos‐Cueva   +8 more
wiley   +1 more source

Balanced centralized and distributed database design in a clinical research environment [PDF]

, 2000
Norman L. Foster, Eszter Gombosi, Cheryl Teboe, Roderick J. A. Little   +3 more
openalex   +1 more source

Multiparadigm design of a simple relational database [PDF]

, 2000
Charles D. Knutson, Timothy A. Budd, Hugh Vidos   +2 more
openalex   +1 more source

On the automation of physical database design [PDF]

Proceedings of the 1993 ACM/SIGAPP symposium on Applied computing states of the art and practice - SAC '93, 1993
Henk Blanken, Sunil Choenni, Thiel Chang
openaire   +4 more sources