Results 101 to 110 of about 1,961,165 (315)

Evaluation of online database selection criteria in electronic scholarly online database: a case study of online databases for business disciplinary in UW-Milwaukee [PDF]

open access: yes, 2021
The academic library has been supported students', and faculties' research works by increasing collections and adding online resources or databases. However, a budget of an academic library has struggled with a shortage.
Lee, Tae Hee
core  

Interpreting the effects of DNA polymerase variants at the structural level

open access: yesMolecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi   +7 more
wiley   +1 more source

Research on Elaboration of an Integrated System Based on Xml Data Analysis [PDF]

open access: yesInformatică economică, 2008
This paper approach the importance of XML for organizing and managing better the data based on texts. This document provides the specification for a data model for describing information organization structures (metadata) for collections of networked ...
Loredana MOCEAN
doaj  

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Database Systems : Design, Implementation, and Management

open access: yes, 2017
Keterampilan database adalah salah satu keterampilan TI yang paling banyak diminati saat ini. Buku ini akan memberikan anda dasar yang kuat dalam desain dan implementasi database dengan pendekatan praktis dan mudah dipahami. Diagram, ilustrasi, dan tabel
Coronel, Carlos, Morris, Steven
core  

LncRNAWiki 2.0: a knowledgebase of human long non-coding RNAs with enhanced curation model and database system. [PDF]

open access: yesNucleic Acids Res, 2022
Liu L   +9 more
europepmc   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

open access: yesMolecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis   +3 more
wiley   +1 more source

Vectorwise: Beyond Column Stores

open access: yes, 2012
This paper tells the story of Vectorwise, a high-performance analytical database system, from multiple perspectives: its history from academic project to commercial product, the evolution of its technical architecture, customer reactions to the product ...
Zukowski, Marcin   +6 more
core  

Home - About - Disclaimer - Privacy