Results 111 to 120 of about 1,961,165 (315)

Creating an Intelligent System for Bankruptcy Detection: Semantic data Analysis Integrating Graph Database and Financial Ontology [PDF]

open access: yes, 2019
In this paper, we propose a novel intelligent methodology to construct a Bankruptcy Prediction Computation Model, which is aimed to execute a company’s financial status analysis accurately.
Yerashenia, N., Bolotov, A.
core  

A Database System with Amnesia. [PDF]

open access: yes, 2017
Big Data comes with huge challenges. Its volume and velocity makes handling, curating, and analytical processing a costly affair. Even to simply “look at” the data within an a priori defined budget and with a guaranteed interactive response time might be impossible to achieve.
M.L. Kersten (Martin)   +1 more
openaire   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

Research on Technology of Database for the Complex Assembly System

open access: yes, 2010
Database technology is the key technology to ensure assembly control data validity, completeness, consistency, security in the complex assembly system. A database model supporting complex assembly system was presented based on the requirement analysis of
Cai YP(蔡云鹏)
core  

Forecasting in Database Systems.

open access: yes, 2014
Time series forecasting is a fundamental prerequisite for decision-making processes and crucial in a number of domains such as production planning and energy load balancing. In the past, forecasting was often performed by statistical experts in dedicated software environments outside of current database systems.
openaire   +3 more sources

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

open access: yesMolecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder   +10 more
wiley   +1 more source

Column-Oriented Database Systems (Tutorial)

open access: yes, 2009
Column-oriented database systems (column-stores) have attracted a lot of attention in the past few years. Column-stores, in a nutshell, store each database table column separately, with attribute values belonging to the same column stored contiguously ...
Abadi, D.   +3 more
core  

MITF maintains genome stability in nonmelanocyte lineages

open access: yesMolecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir   +13 more
wiley   +1 more source

DATABASE DEVELOPMENT LIFE CYCLE [PDF]

open access: yes
A software development life cycle model (SDLC) consists of a set of processes (planning, requirements, design, development, testing, installation and maintenance) defined to accomplish the task of developing a software application that is functionally ...
Morgan D. Monger   +2 more
core  

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