Results 121 to 130 of about 1,961,165 (315)
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
IPD - the Immuno Polymorphism Database
, 2005 The Immuno Polymorphism Database (IPD) (http://www.ebi.ac.uk/ipd/) is a set of specialist databases related to the study of polymorphic genes in the immune system.
Marsh, S.G.E. +3 more
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Incremental Data Migration for Multi-Database Systems [PDF]
, 2012 Nowadays, database systems are one of the most popular and essential software programs in computer systems. Many computers are installed a database system and users maybe want to use these database systems as one system.
HIGUCHI, Ken +2 more
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Foundations of Preferences in Database Systems [PDF]
, 2002 Personalization of e-services poses new challenges to database technology, demanding a powerful and flexible modeling technique for complex preferences. Preference queries have to be answered cooperatively by treating preferences as soft constraints, attempting a best possible match-making.
openaire +2 more sources
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Rigorous Design of Fault-Tolerant Transactions for Replicated Database Systems using Event B
, 2006 System availability is improved by the replication of data objects in a distributed database system. However, during updates, the complexity of keeping replicas identical arises due to failures of sites and race conditions among conflicting transactions.
Yadav, Divakar, Butler, Michael
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Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis
Molecular Oncology, EarlyView.This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht +3 more
wiley +1 more source
A dubiety-determining based model for database cumulated anomaly intrusion
, 2007 The concept of Cumulated Anomaly (CA), which describes a new type of database anomalies, is addressed. A typical CA intrusion is that when a user who is authorized to modify data records under certain constraints deliberately hides his/her intentions ...
Yi, J +5 more
core +1 more source
Molecular Oncology, EarlyView.Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski +12 more
wiley +1 more source
Revolutionary Database Technology for Data Intensive Research [PDF]
, 2012 The ability to explore huge digital resources assembled in data warehouses, databases and files, at unprecedented speed, is becoming the driver of progress in science.
Manegold, S. (Stefan) +5 more
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