Results 121 to 130 of about 22,995,424 (299)
A Database System with Amnesia.
, 2017 Big Data comes with huge challenges. Its volume and velocity makes handling, curating, and analytical processing a costly affair. Even to simply “look at” the data within an a priori defined budget and with a guaranteed interactive response time might be impossible to achieve.
M.L. Kersten (Martin) +1 more
openaire +2 more sources
Molecular Oncology, EarlyView.This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi +6 more
wiley +1 more source
Unraveling the epigenetic code in cancer cell–tumor microenvironment crosstalk
Molecular Oncology, EarlyView.Epigenetic regulation is a key driver of cancer development and progression. Diverse epigenetic alterations in cancer cells and components of the tumor microenvironment (TME) orchestrate their communication through multiple mechanisms. We discuss how the epigenetic code coordinates bidirectional cancer cell–TME crosstalk to promote cancer progression ...
Ji Hoon Park, Mi‐Young Kim
wiley +1 more source
Molecular Oncology, EarlyView.This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic +10 more
wiley +1 more source
Object-oriented modeling and design of database federations [PDF]
We describe a logical architecture and a general semantic framework for precise specification of so-called database federations. A database federation provides for tight coupling of a collection of heterogeneous component databases into a global ...
Balsters, H.
core
Rigorous Design of Fault-Tolerant Transactions for Replicated Database Systems using Event B
, 2006 System availability is improved by the replication of data objects in a distributed database system. However, during updates, the complexity of keeping replicas identical arises due to failures of sites and race conditions among conflicting transactions.
Yadav, Divakar, Butler, Michael
core +1 more source
The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer
Molecular Oncology, EarlyView.Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad +2 more
wiley +1 more source
Database Systems : Design, Implementation, and Management
, 2017 Keterampilan database adalah salah satu keterampilan TI yang paling banyak diminati saat ini. Buku ini akan memberikan anda dasar yang kuat dalam desain dan implementasi database dengan pendekatan praktis dan mudah dipahami. Diagram, ilustrasi, dan tabel
Coronel, Carlos, Morris, Steven
core
Artificial Intelligence Research: The Utility and Design of a Relational Database System. [PDF]
Adv Radiat Oncol, 2020 Dilling TJ.
europepmc +1 more source
Molecular Oncology, EarlyView.High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira +7 more
wiley +1 more source