Results 41 to 50 of about 1,088,169 (316)
A storage and access architecture for efficient query processing in spatial database systems [PDF]
, 1993 Due to the high complexity of objects and queries and also due to extremely large data volumes, geographic database systems impose stringent requirements on their storage and access architecture with respect to efficient query processing.
Kriegel, Hans-Peter +8 more
core +1 more source
Processing of the geological documentation using CAD systems and GIS [PDF]
Acta Montanistica Slovaca, 1998 World-wide trend of geological data processing leaves old documentation forms and shows the necessity for introduction of computer technologies utilising GIS and CAD systems for the processing of geological documentation.
Grinč Anton, Blišťan Peter
doaj
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
FoPA: identifying perturbed signaling pathways in clinical conditions using formal methods
BMC Bioinformatics, 2019 Background Accurate identification of perturbed signaling pathways based on differentially expressed genes between sample groups is one of the key factors in the understanding of diseases and druggable targets.
Fatemeh Mansoori +2 more
doaj +1 more source
Approximations in Database Systems
, 2002 The need for approximations of information has become very critical in the recent past. From traditional query optimization to newer functionality like user feedback and knowledge discovery, data management systems require quick delivery of approximate data in order to serve their goals. There are several techniques that have been proposed to solve the
openaire +2 more sources
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Machine Learning and Knowledge ExtractionIn data-driven systems, data exploration is imperative for making real-time decisions. However, big data are stored in massive databases that are difficult to retrieve.
Mohammadali Fallahian +2 more
doaj +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Revolutionary Database Technology for Data Intensive Research [PDF]
, 2012 The ability to explore huge digital resources assembled in data warehouses, databases and files, at unprecedented speed, is becoming the driver of progress in science.
Manegold, S. (Stefan) +5 more
core
Human Genome VariationLarge language models (LLMs) have recently been adopted to assist in the interpretation of human genomic variants. However, general-purpose LLMs can produce incorrect outputs (commonly termed ‘hallucinations’), particularly on specialized queries ...
Nobutaka Mitsuhashi +2 more
doaj +1 more source