Results 51 to 60 of about 1,088,169 (316)
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Diagnosis of Alzheimer’s disease with high accuracy via Petri net modeling of signaling pathways
Scientific ReportsAlzheimer’s disease is a complex disorder of the nervous system. Diagnosing this disease is a costly process in which numerous laboratory tests and examinations are conducted.
Hananeh Ebrahimian +3 more
doaj +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
On the Benefits of Non-Canonical Filtering in Publish/Subscribe Systems
, 2005 Current matching approaches in pub/sub systems only allow conjunctive subscriptions. Arbitrary subscriptions have to be transformed into canonical expressions, e.g., DNFs, and need to be treated as several conjunctive subscriptions.
Bittner, Sven +3 more
core +1 more source
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
Incremental Data Migration for Multi-Database Systems [PDF]
, 2012 Nowadays, database systems are one of the most popular and essential software programs in computer systems. Many computers are installed a database system and users maybe want to use these database systems as one system.
HIGUCHI, Ken +2 more
core
Database-Assisted Spectrum Sharing in Satellite Communications: A Survey
IEEE Access, 2017 This survey paper discusses the feasibility of sharing the spectrum between satellite telecommunication networks and terrestrial and other satellite networks on the basis of a comprehensive study carried out as part of the European Space Agency's ...
Marko Hoyhtya +6 more
doaj +1 more source
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
FEBS Letters, EarlyView.Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
Integrating Informatics Technologies into Oracle [PDF]
Informatică economică, 2006 A characteristic of the actual informatics’ context is the interference of the technologies, which assumes that for creating an informatics product, is necessary to use integrate many technologies.
Manole VELICANU
doaj
Energy Science & Engineering, 2019 Biodiesel fuel and biogas fuel as promising alternative energy sources for dual‐fuel‐mode diesel engine attract more researchers. Therefore, this study highlights the dual‐fuel mode (DFM) operation of diesel engine using biodiesel fuel from used cooking ...
Yoshihiko Oishi +4 more
doaj +1 more source