Results 51 to 60 of about 3,107,135 (285)

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Diagnosis of Alzheimer’s disease with high accuracy via Petri net modeling of signaling pathways

open access: yesScientific Reports
Alzheimer’s disease is a complex disorder of the nervous system. Diagnosing this disease is a costly process in which numerous laboratory tests and examinations are conducted.
Hananeh Ebrahimian   +3 more
doaj   +1 more source

An Expert System for Managing an Activated Sludge Wastewater Treatment Plant [PDF]

open access: yes, 1989
A diagnostic expert system for an activated sludge wastewater treatment plant has been designed to link with a relational database management system for obtaining operational parameter values that are used by the program to diagnose operational problems ...
Parker, David G., Parker, Sandra C.
core   +2 more sources

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

The Impact of Global Clustering on Spatial Database Systems [PDF]

open access: yes, 1994
Global clustering has rarely been investigated in the area of spatial database systems although dramatic performance improvements can be achieved by using suitable techniques.
Brinkhoff, Thomas, Kriegel, Hans-Peter
core   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Integrating Informatics Technologies into Oracle [PDF]

open access: yesInformatică economică, 2006
A characteristic of the actual informatics’ context is the interference of the technologies, which assumes that for creating an informatics product, is necessary to use integrate many technologies.
Manole VELICANU
doaj  

Performance, rate of heat release, and combustion stability of dual‐fuel mode in a small diesel engine

open access: yesEnergy Science & Engineering, 2019
Biodiesel fuel and biogas fuel as promising alternative energy sources for dual‐fuel‐mode diesel engine attract more researchers. Therefore, this study highlights the dual‐fuel mode (DFM) operation of diesel engine using biodiesel fuel from used cooking ...
Yoshihiko Oishi   +4 more
doaj   +1 more source

Database-Assisted Spectrum Sharing in Satellite Communications: A Survey

open access: yesIEEE Access, 2017
This survey paper discusses the feasibility of sharing the spectrum between satellite telecommunication networks and terrestrial and other satellite networks on the basis of a comprehensive study carried out as part of the European Space Agency's ...
Marko Hoyhtya   +6 more
doaj   +1 more source

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