Results 41 to 50 of about 8,945,205 (302)
A machine learning framework for elastic constants predictions in multi-principal element alloys
APL Machine Learning, 2023 On the one hand, multi-principal element alloys (MPEAs) have created a paradigm shift in alloy design due to large compositional space, whereas on the other, they have presented enormous computational challenges for theory-based materials design ...
Nathan Linton, Dilpuneet S. Aidhy
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Defence Technology, 2022 Loitering munitions are increasingly used in armed conflicts. An extensive database of loitering munitions is developed based on information available in the public domain.
Mark Voskuijl
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Molecular bases of circadian magnesium rhythms across eukaryotes
FEBS Letters, EarlyView.Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley +1 more source
Historical Life Course Studies, 2021 The role played by midwives during modernity deserves increased attention. Ethnic and confessional minorities often displayed starkly different patterns in the selection of these instrumental figures. More than that, the differences between the official
Luminiţa Dumănescu, Ioan Bolovan
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Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
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CLASSIFICATION OF LOGICAL DATA MODELS IMPLEMENTED BY CONTEMPORARY DBMS
Cifra: Информационные технологии и телекоммуникацииApart from relational model, many contemporary DBMS implement different data models, including extensions of relational ones. Most of DBMS implement also multiple data models, and are so called “multi-model”.
Tarassov S.
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Providing Sustainable Supply Chain Agility Model in the Brick Industry of Isfahan province [PDF]
مدیریت صنعتی, 2018 Objective: Today, manufacturing companies must pay attention to environmental and social issues throughout the supply chain in order to survive. Many efforts have been made to examine the sustainable supply chain, but the agility of sustainable supply ...
Farhad Farhadi +3 more
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Aggressive prostate cancer is associated with pericyte dysfunction
Molecular Oncology, EarlyView.Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero +11 more
wiley +1 more source
Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Molecular Oncology, EarlyView.Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed +10 more
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