Results 61 to 70 of about 9,892,012 (315)
Translophagy—A potential link between autophagy impairment and translational errors
FEBS Letters, EarlyView.Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
How Database Theory Helps Teach Relational Queries in Database Education (Invited Talk)
Data analytics skills have become an indispensable part of any education that seeks to prepare its students for the modern workforce. Essential in this skill set is the ability to work with structured relational data.
Gilad, Amir +6 more
core +1 more source
Integrating Fuzzy Decisioning Models With Relational Database Constructs
, 2016 Human learning and classification is a nebulous area in computer science. Classic decisioning problems can be solved given enough time and computational power, but discrete algorithms cannot easily solve fuzzy problems. Fuzzy decisioning can resolve more
Durham, Erin-Elizabeth A
core +1 more source
RAM Legacy Stock Assessment Database v4.61
, 2023 RAM Legacy Stock Assessment Database version 4 ...
RAM Legacy Stock Assessment Database
core +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Serializability theory for replicated databases
Journal of Computer and System Sciences, 1985 In a one-copy distributed database, each data item is stored at exactly one site of a distributed system. In a replicated database, some data items are stored at multiple sites. The main motivation for replicated data is improved reliability: by storing important data at multiple sites, the system can tolerate failures more gracefully.
Philip A. Bernstein, Nathan Goodman
openaire +3 more sources
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Microkinetics of alcohol reforming for H2 production from a FAIR density functional theory database
Nature Communications, 2018 The production of hydrogen from biomass is of fundamental importance for a sustainable future. Here, the authors present a multiscale method that allows the formulation of scaling relationships and microkinetics of C1-C2 alcohol decomposition based on a ...
Qiang Li +2 more
doaj +1 more source
Column-Oriented Database Systems (Tutorial) [PDF]
, 2009 Column-oriented database systems (column-stores) have attracted a lot of attention in the past few years. Column-stores, in a nutshell, store each database table column separately, with attribute values belonging to the same column stored contiguously ...
Abadi, D. +3 more
core
Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source