Results 71 to 80 of about 287,498 (311)

Database Queries that Explain their Work [PDF]

open access: yes, 2014
Provenance for database queries or scientific workflows is often motivated as providing explanation, increasing understanding of the underlying data sources and processes used to compute the query, and reproducibility, the capability to recompute the ...
Cheney, James   +7 more
core   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Visualization of database structures for information retrieval [PDF]

open access: yes, 1994
This paper describes the Book House system, which is designed to support children's information retrieval in libraries as part of their education. It is a shareware program available on CD‐ROM or floppy disks, and comprises functionality for database ...
Lisbjerg Jensen, G.   +11 more
core   +1 more source

Microkinetics of alcohol reforming for H2 production from a FAIR density functional theory database

open access: yesNature Communications, 2018
The production of hydrogen from biomass is of fundamental importance for a sustainable future. Here, the authors present a multiscale method that allows the formulation of scaling relationships and microkinetics of C1-C2 alcohol decomposition based on a ...
Qiang Li   +2 more
doaj   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Smarter searching for a network packet database [PDF]

open access: yes, 2010
Bioinformatics has developed some very sophisticated algorithms used for searching within the large amounts of data produced by sequencing projects. Introduced here is a method that leverages these algorithms for processing computer network data traffic ...
William D. Kenworthy, Kenworthy, W.D.
core   +2 more sources

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Feature Structures and Database Theory [PDF]

open access: yes, 1995
More and more often, computational linguists and language engineers need to manipulate large sets of feature structures which constitute real databases. Creating, updating, querying and in general, exploiting such linguistic databases is not an easy task,
Jean Véronis
core  

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

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