Understanding Collaboration: Introducing the Collaborative Governance Case Databank
Policy & Society, 2020 Studying collaborative governance has become abooming business. However, the empirical literature still struggles to produce robust generalizations and cumulative knowledge that link contextual, situational and institutional design factors to processes ...
Scott Douglas +5 more
doaj +1 more source
A working model for cytoplasmic assembly of H/ACA snoRNPs
FEBS Letters, EarlyView.Dyskerin is the component of nuclear H/ACA ribonucleoproteins (RNPs) endowed with pseudouridine synthase catalytic activity. Two isoforms of human dyskerin have been characterized: the abundant Iso1, mainly nuclear, and the shorter Iso3, mainly cytoplasmic but occasionally imported into nuclei.
Alberto Angrisani, Maria Furia
wiley +1 more source
A Generative Model for Score Normalization in Speaker Recognition
, 2017 We propose a theoretical framework for thinking about score normalization, which confirms that normalization is not needed under (admittedly fragile) ideal conditions. If, however, these conditions are not met, e.g.
Brummer, Niko, Swart, Albert
core +1 more source
FEBS Letters, EarlyView.Single‐cell RNA sequencing reveals an opposite role of SLPI in basal tumors based on metastatic spread, along with shared activation of specific regulons in cancer cells and mature luminal lactocytes, as well as downregulation of MALAT1 and NEAT1 in the latter.
Pietro Ancona +4 more
wiley +1 more source
Cancer cell death induced by the NAD antimetabolite Vacor discloses the antitumor potential of SARM1
FEBS Letters, EarlyView.Vacor, a compound converted into the toxic metabolite Vacor adenine dinucleotide (VAD) by the nicotinamide salvage pathway enzymes NAMPT and NMNAT2, exhibits antitumor activity by inducing rapid and complete NAD depletion. We report that Vacor toxicity is limited to cell lines expressing high levels of SARM1, a NAD glycohydrolase.
Giuseppe Ranieri +5 more
wiley +1 more source
Functional dependencies for XML : axiomatisation and normal form in the presence of frequencies and identifiers : a thesis presented in partial fulfilment of the requirements for the degree of Master of Sciences in Information Sciences at Massey University, Palmerston North, New Zealand [PDF]
, 2005 XML has gained popularity as a markup language for publishing and exchanging data on the web. Nowadays, there are also ongoing interests in using XML for representing and actually storing data. In particular, much effort has been directed towards turning
Trinh, Diem-Thu
core
An intracellular transporter mitigates the CO2‐induced decline in iron content in Arabidopsis shoots
FEBS Letters, EarlyView.This study identifies a gene encoding a transmembrane protein, MIC, which contributes to the reduction of shoot Fe content observed in plants under elevated CO2. MIC is a putative Fe transporter localized to the Golgi and endosomal compartments. Its post‐translational regulation in roots may represent a potential target for improving plant nutrition ...
Timothy Mozzanino +7 more
wiley +1 more source
The Monomer Electron Density Force Field (MEDFF) : a physically inspired model for noncovalent interactions [PDF]
, 2016 We propose a methodology to derive pairwise-additive noncovalent force fields from monomer electron densities without any empirical input. Energy expressions are based on the symmetry-adapted perturbation theory (SAPT) decomposition of interaction ...
Van Speybroeck, Veronique +3 more
core +3 more sources
FEBS Letters, EarlyView.Anaplastic thyroid cancer (ATC) lacks iodide uptake ability due to MAPK activation increasing the expression of the histone methyltransferase EZH2, which represses thyroid differentiation genes (TDGs) such as the sodium iodide symporter (NIS). Dual inhibition of MAPK (U0126) and EZH2 (EPZ6438/Tazemetostat) reverses this mechanism, thus restoring TDG ...
Diego Claro de Mello +6 more
wiley +1 more source
A database of computed Raman spectra of inorganic compounds with accurate hybrid functionals
Scientific DataRaman spectroscopy is widely applied in identifying local structures in materials, but the interpretation of Raman spectra is non-trivial. An accurate computational database of reference spectra calculated with a consistent level of theory can ...
Yuheng Li +5 more
doaj +1 more source