Results 101 to 110 of about 654,837 (328)
C6orf10 low-frequency and rare variants in italian multiple sclerosis patients [PDF]
, 2019 In light of the complex nature of multiple sclerosis (MS) and the recently estimated contribution of low-frequency variants into disease, decoding its genetic risk components requires novel variant prioritization strategies.
Balestra, Dario +16 more
core +2 more sources
Molecular Oncology, EarlyView.VASP was found to be overexpressed in metastatic oral squamous cell carcinoma (OSCC) tissues. Notably, PTTG1‐ and VASP‐deficient OSCC cells demonstrated suppressed metastatic properties by disrupting the interaction between the cytoskeleton and focal adhesion (FAs) in the filopodia region.
Suyeon Park +6 more
wiley +1 more source
An investigation of genetic algorithm-based feature selection techniques applied to keystroke dynamics biometrics [PDF]
, 2019 Due to the continuous use of social networks, users can be vulnerable to online situations such as paedophilia treats. One of the ways to do the investigation of an alleged pedophile is to verify the legitimacy of the genre that it claims. One possible
Da Costa Abreu, Marjory +3 more
core
Comparative genomic analysis of Acinetobacter spp. plasmids originating from clinical settings and environmental habitats [PDF]
, 2018 Bacteria belonging to the genus Acinetobacter have become of clinical importance over the last decade due to the development of a multi-resistant phenotype and their ability to survive under multiple environmental conditions.
Pistorio, Mariano +5 more
core +2 more sources
Molecular Oncology, EarlyView.Tumor microenvironment drives cancer formation and progression. We analyzed the role of human cancer‐associated adipocytes from patients with renal cell carcinoma (RCC) stratified as lean, overweight, or obese. RNA‐seq demonstrated that, among the most altered genes involved in the tumor–stroma crosstalk, are ADAM12 and CYP1B1, which were proven to be ...
Sepehr Torabinejad +13 more
wiley +1 more source
Performing the Union: the Prüm Decision and the European dream [PDF]
, 2012 In 2005, seven European countries signed the so-called Prüm Treaty to increase transnational collaboration in combating international crime, terrorism and illegal immigration. Three years later, the Treaty was adopted into EU law. EU member countries are
Agamben +41 more
core +1 more source
KMT2A degradation is observed in decitabine‐responsive acute lymphoblastic leukemia cells
Molecular Oncology, EarlyView.We demonstrate that decitabine (DEC) not only degrades the DNA methyltransferase DNMT1 but also the leukemic driver lysine methyltransferase KMT2A likely due to structural similarity of the DNA‐binding CXXC domains. DEC influences KMT2A downstream processes and synergizes with menin inhibitor revumenib (REV) to decrease leukemic cell proliferation, and
Luisa Brock +10 more
wiley +1 more source
Construction and Functional Analysis of Human Genetic Interaction Networks with Genome-wide Association Data [PDF]
arXiv, 2011 Genetic interaction measures how different genes collectively contribute to a phenotype, and can reveal functional compensation and buffering between pathways under genetic perturbations. Recently, genome-wide screening for genetic interactions has revealed genetic interaction networks that provide novel insights either when analyzed by themselves or ...
arxiv
Mare Geneticum : Balancing Governance of Marine Genetic Resources in International Waters [PDF]
, 2018 Peer reviewedPublisher ...
Broggiato, Arianna +5 more
core +2 more sources
Genomic and Genetic Database Resources for the Grasses [PDF]
Plant Physiology, 2009 In the strict sense, a biological database is not a Web site. However, the interface that a researcher uses to access the data stored within a database is almost always a Web site. Nonetheless, the two terms are synonymous in the minds of most biologists.
openaire +3 more sources