Results 141 to 150 of about 5,268,956 (336)
Acquisition and retention of DNA and fingerprint data in Scotland [PDF]
, 2009 This review examines the current legislation and practices in relation to the acquisition and retention of fingerprint and DNA data in Scotland. Three main issues were under consideration: given that law and practice in relation to DNA and fingerprints ...
Fraser, Jim +1 more
core
EMT‐associated bias in the Parsortix® system observed with pancreatic cancer cell lines
Molecular Oncology, EarlyView.The Parsortix® system was tested for CTC enrichment using pancreatic cancer cell lines with different EMT phenotypes. Spike‐in experiments showed lower recovery of mesenchymal‐like cells. This was confirmed with an EMT‐inducible breast cancer cell line.
Nele Vandenbussche +8 more
wiley +1 more source
Molecular Oncology, EarlyView.Cotargeting EGFR and STAT3 with Erlotinib and TTI‐101 impairs both 2D and 3D growth of ETV1‐overexpressing prostate cancer cells by disrupting a self‐sustaining ETV1–EGFR positive feedback loop that promotes EGFR and STAT3 expression and phosphorylation (activation).
Elsa Gomes Paiva +5 more
wiley +1 more source
Pathway-Based Drug Repositioning for Breast Cancer Molecular Subtypes
Frontiers in Pharmacology, 2018 Breast cancer is a major public health problem which treatment needs new pharmacological options. In the last decades, during the postgenomic era new theoretical and technological tools that give us novel and promising ways to address these problems have
Raúl A. Mejía-Pedroza +4 more
doaj +1 more source
Genetic databases and donor anonymity [PDF]
Human Reproduction, 2019 Kennett, D, Reisel, D, Harper, J
openaire +4 more sources
, 2010 Motivation: Signaling pathways control a large variety of cellular processes. However, currently, even within the same database signaling pathways are often curated at different levels of detail.
Amberger +65 more
core +1 more source
Molecular Oncology, EarlyView.In luminal (ER+) breast carcinoma (BC), miRNA profiling identified miR‐195‐5p as a key regulator of proliferation that targets CHEK1, CDC25A, and CCNE1. High CHEK1 expression correlates with worse relapse‐free survival after chemotherapy, especially in patients with luminal A subtype.
Veronika Boušková +14 more
wiley +1 more source
Molecular Oncology, EarlyView.In thyroid cancer patients, high‐dose (≥7.4 GBq) radioactive iodine therapy (RAIT) was associated with a higher prevalence of clonal hematopoiesis (variant allele frequency >2%) in individuals aged ≥50 years (OR = 2.44). In silico analyses showed that truncating PPM1D mutations conferred a selective advantage under these conditions.
Jaeryuk Kim +11 more
wiley +1 more source
Opportunities and Challenges for Genetic Studies of End-Stage Renal Disease in Canada
Canadian Journal of Kidney Health and Disease, 2018 Purpose of review: Genetic testing can improve diagnostic precision in some patients with end-stage renal disease (ESRD) providing the potential for targeted therapy and improved patient outcomes.
Vinusha Kalatharan +2 more
doaj +1 more source
NIASGBdb: NIAS Genebank databases for genetic resources and plant disease information
Nucleic Acids Res., 2010 The National Institute of Agrobiological Sciences (NIAS) is implementing the NIAS Genebank Project for conservation and promotion of agrobiological genetic resources to contribute to the development and utilization of agriculture and agricultural ...
Masaru Takeya +9 more
semanticscholar +1 more source