Subquery allocations in distributed databases using genetic algorithms
Minimization of query execution time is an important performance objective in distributed databases design. While total time is to be minimized for On Line Transaction Processing (OLTP) type queries, response time has to be minimized in Decision Support ...
Narasimhaiah Gorla, Suk-Kyu Song
doaj
Geospatial distribution and population substructure of subgroups of US ethnic minorities: implications for perpetuation of health disparities and paucity of precision medicine [PDF]
Substructure due to familial-associated divisions exists in all large populations. Geographical heterogeneity in US ethnic minorities is a function of historical, social, political, and economic factors overlaying regional geographical biodiversity ...
Jackson, Fatimah L.C., Jackson, Hasan
core +1 more source
A comparative study of circulating tumor cell isolation and enumeration technologies in lung cancer
Lung cancer cells were spiked into donor blood to evaluate the recovery rates of the following circulating tumor cell (CTC) enrichment technologies: CellMag™, EasySep™, RosetteSep™, Parsortix® PR1, and Parsortix® Prototype systems. Each method's advantages and disadvantages are described.
Volga M Saini+11 more
wiley +1 more source
Computation of Diet Composition for Patients Suffering from Kidney and Urinary Tract Diseases with the Fuzzy Genetic System [PDF]
Determination of dietary food consumed a day for patients with diseases in general, greatly affect the health of the body and the healing process, is no exception for people with kidney disease and urinary tract. This paper presents the determination of diet composition in the form of food subtance for people with kidney and urinary tract diseases with
arxiv +1 more source
Cell‐free and extracellular vesicle microRNAs with clinical utility for solid tumors
Cell‐free microRNAs (cfmiRs) are small‐RNA circulating molecules detectable in almost all body biofluids. Innovative technologies have improved the application of cfmiRs to oncology, with a focus on clinical needs for different solid tumors, but with emphasis on diagnosis, prognosis, cancer recurrence, as well as treatment monitoring.
Yoshinori Hayashi+6 more
wiley +1 more source
Utilising public sequence databases to investigate genetic diversity of stoneflies in Medvednica Nature Park [PDF]
In Medvednica Nature Park, near Croatia's capital Zagreb, urbanisation significantly impacts the fauna. Comprehensive field research has never been conducted in this area, despite the presence of diverse microhabitats and the discovery of several rare ...
Dora Kermek+4 more
doaj +3 more sources
PharmaKoVariome database for supporting genetic testing
AbstractPharmacogenomics (PGx) provides information about routine precision medicine, based on the patient’s genotype. However, many of the available information about human allele frequencies, and about clinical drug–gene interactions, is based on American and European populations.
Jungeun Kim+3 more
openaire +3 more sources
This study demonstrates that KRAS and GNAS mutations are more prevalent in patients with resected intraductal papillary mucinous neoplasms (IPMN) compared to those under clinical surveillance. GNAS mutations significantly differ between the two patient cohorts, indicating that their absence may serve as a potential biomarker to support conservative ...
Christine Nitschke+12 more
wiley +1 more source
Genetic ancestry plays a central role in population pharmacogenomics
Hsin-Chou Yang et al. examine population structure in several genomic databases and identify that pharmacogenetic loci are enriched for markers of genetic ancestry.
Hsin-Chou Yang+3 more
doaj +1 more source
Understanding and predicting synthetic lethal genetic interactions in Saccharomyces cerevisiae using domain genetic interactions [PDF]
Genetic interactions have been widely used to define functional relationships between proteins and pathways. In this study, we demonstrated that yeast synthetic lethal genetic interactions can be explained by the genetic interactions between domains of those proteins.
arxiv