Results 21 to 30 of about 8,370,207 (250)

SwissPalm: Protein Palmitoylation database [PDF]

open access: yesF1000Research, 2015
Protein S-palmitoylation is a reversible post-translational modification that regulates many key biological processes, although the full extent and functions of protein S-palmitoylation remain largely unexplored. Recent developments of new chemical methods have allowed the establishment of palmitoyl-proteomes of a variety of cell lines and tissues from
Mathieu Blanc   +6 more
openaire   +2 more sources

Current successes and remaining challenges in protein function prediction

open access: yesFrontiers in Bioinformatics, 2023
In recent years, improvements in protein function prediction methods have led to increased success in annotating protein sequences. However, the functions of over 30% of protein-coding genes remain unknown for many sequenced genomes.
Constance J. Jeffery
doaj   +1 more source

Tandem repeats lead to sequence assembly errors and impose multi-level challenges for genome and protein databases

open access: yesNucleic Acids Research, 2019
The widespread occurrence of repetitive stretches of DNA in genomes of organisms across the tree of life imposes fundamental challenges for sequencing, genome assembly, and automated annotation of genes and proteins.
O. K. Tørresen   +12 more
semanticscholar   +1 more source

The impact of sequence database choice on metaproteomic results in gut microbiota studies [PDF]

open access: yes, 2016
Background: Elucidating the role of gut microbiota in physiological and pathological processes has recently emerged as a key research aim in life sciences.
Addis, Maria Filippa   +10 more
core   +4 more sources

ProteoClade: A taxonomic toolkit for multi-species and metaproteomic analysis [PDF]

open access: yes, 2020
We present ProteoClade, a Python toolkit that performs taxa-specific peptide assignment, protein inference, and quantitation for multi-species proteomics experiments.
Held, Jason M   +3 more
core   +2 more sources

Uniclust databases of clustered and deeply annotated protein sequences and alignments

open access: yesNucleic Acids Res., 2016
We present three clustered protein sequence databases, Uniclust90, Uniclust50, Uniclust30 and three databases of multiple sequence alignments (MSAs), Uniboost10, Uniboost20 and Uniboost30, as a resource for protein sequence analysis, function prediction ...
M. Mirdita   +5 more
semanticscholar   +1 more source

Databases in Protein Crystallography [PDF]

open access: yesActa Crystallographica Section D Biological Crystallography, 1998
Applications of structural databases in the protein crystallographic structure determination process are reviewed, using mostly examples from work carried out by the authors. Four application areas are discussed: model building, model refinement, model validation and model analysis.
G J, Kleywegt, T A, Jones
openaire   +2 more sources

Gene and protein nomenclature in public databases

open access: yesBMC Bioinformatics, 2006
Background Frequently, several alternative names are in use for biological objects such as genes and proteins. Applications like manual literature search, automated text-mining, named entity identification, gene/protein annotation, and linking of ...
Zimmer Ralf, Fundel Katrin
doaj   +1 more source

An analysis of the Sargasso Sea resource and the consequences for database composition [PDF]

open access: yes, 2006
Background: The environmental sequencing of the Sargasso Sea has introduced a huge new resource of genomic information. Unlike the protein sequences held in the current searchable databases, the Sargasso Sea sequences originate from a single marine ...
Cozzetto, D   +3 more
core   +4 more sources

The Pfam Protein Families Database [PDF]

open access: yesNucleic Acids Research, 2000
Pfam is a large collection of protein families and domains. Over the past 2 years the number of families in Pfam has doubled and now stands at 6190 (version 10.0). Methodology improvements for searching the Pfam collection locally as well as via the web are described.
Bateman, Alex   +12 more
openaire   +7 more sources

Home - About - Disclaimer - Privacy