Results 21 to 30 of about 666,912 (235)
MODBASE, a database of annotated comparative protein structure models and associated resources. [PDF]
MODBASE (http://salilab.org/modbase) is a database of annotated comparative protein structure models. The models are calculated by MODPIPE, an automated modeling pipeline that relies primarily on MODELLER for fold assignment, sequence-structure alignment,
Barkan, David T+11 more
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A Molecular Biology Database Digest [PDF]
Computational Biology or Bioinformatics has been defined as the application of mathematical and Computer Science methods to solving problems in Molecular Biology that require large scale data, computation, and analysis [18].
Bry, François, Kröger, Peer
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BindingDB in 2015: A public database for medicinal chemistry, computational chemistry and systems pharmacology. [PDF]
BindingDB, www.bindingdb.org, is a publicly accessible database of experimental protein-small molecule interaction data. Its collection of over a million data entries derives primarily from scientific articles and, increasingly, US patents.
Baitaluk, Michael+5 more
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The Pfam protein families database [PDF]
Pfam is a widely used database of protein families and domains. This article describes a set of major updates that we have implemented in the latest release (version 24.0). The most important change is that we now use HMMER3, the latest version of the popular profile hidden Markov model package.
Finn, Robert D.+13 more
openaire +4 more sources
MedProDB: A database of Mediator proteins
In the last three decades, the multi-subunit Mediator complex has emerged as the key component of transcriptional regulation of eukaryotic gene expression. Although there were initial hiccups, recent advancements in bioinformatics tools contributed significantly to in-silico prediction and characterization of Mediator subunits from several organisms ...
Rohan Bhardwaj+2 more
openaire +3 more sources
ppiTrim: Constructing non-redundant and up-to-date interactomes [PDF]
Robust advances in interactome analysis demand comprehensive, non-redundant and consistently annotated datasets. By non-redundant, we mean that the accounting of evidence for every interaction should be faithful: each independent experimental support is ...
Stojmirović, Aleksandar, Yu, Yi-Kuo
core +3 more sources
An analysis of the Sargasso Sea resource and the consequences for database composition [PDF]
Background: The environmental sequencing of the Sargasso Sea has introduced a huge new resource of genomic information. Unlike the protein sequences held in the current searchable databases, the Sargasso Sea sequences originate from a single marine ...
Cozzetto, D+3 more
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SwissPalm: Protein Palmitoylation database [PDF]
Protein S-palmitoylation is a reversible post-translational modification that regulates many key biological processes, although the full extent and functions of protein S-palmitoylation remain largely unexplored. Recent developments of new chemical methods have allowed the establishment of palmitoyl-proteomes of a variety of cell lines and tissues from
Mathieu Blanc+6 more
openaire +4 more sources
Data access and integration in the ISPIDER proteomics grid [PDF]
Grid computing has great potential for supporting the integration of complex, fast changing biological data repositories to enable distributed data analysis.
C.A. Goble+12 more
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Ontology-assisted database integration to support natural language processing and biomedical data-mining [PDF]
Successful biomedical data mining and information extraction require a complete picture of biological phenomena such as genes, biological processes, and diseases; as these exist on different levels of granularity.
Ceusters, Werner+4 more
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