Results 21 to 30 of about 497,683 (263)

The Protein-DNA Interface database [PDF]

open access: yesBMC Bioinformatics, 2010
The Protein-DNA Interface database (PDIdb) is a repository containing relevant structural information of Protein-DNA complexes solved by X-ray crystallography and available at the Protein Data Bank. The database includes a simple functional classification of the protein-DNA complexes that consists of three hierarchical levels: Class, Type and Subtype ...
Norambuena Arenas, Tomás.   +1 more
openaire   +6 more sources

Optimizing metaproteomics database construction: lessons from a study of the vaginal microbiome

open access: yesmSystems, 2023
Metaproteomics, a method for untargeted, high-throughput identification of proteins in complex samples, provides functional information about microbial communities and can tie functions to specific taxa.
Elliot M. Lee   +8 more
doaj   +1 more source

Mining Protein Databases using Machine Learning Techniques

open access: yesJournal of Integrative Bioinformatics, 2008
With a large amount of information relating to proteins accumulating in databases widely available online, it is of interest to apply machine learning techniques that, by extracting underlying statistical regularities in the data, make predictions about ...
Camargo Renata da Silva   +1 more
doaj   +1 more source

Improving classification in protein structure databases using text mining

open access: yesBMC Bioinformatics, 2009
Background The classification of protein domains in the CATH resource is primarily based on structural comparisons, sequence similarity and manual analysis.
Jones David T   +2 more
doaj   +1 more source

Mapping OMIM Disease–Related Variations on Protein Domains Reveals an Association Among Variation Type, Pfam Models, and Disease Classes

open access: yesFrontiers in Molecular Biosciences, 2021
Human genome resequencing projects provide an unprecedented amount of data about single-nucleotide variations occurring in protein-coding regions and often leading to observable changes in the covalent structure of gene products.
Castrense Savojardo   +4 more
doaj   +1 more source

The PIR integrated protein databases and data retrieval system

open access: yesData Science Journal, 2006
The Protein Information Resource (PIR) provides many databases and tools to support genomic and proteomic research. PIR is a member of UniProt—Universal Protein Resource—the central repository of protein sequence and function, which maintains UniProt ...
H Huang, ZZ Hu, BE Suzek, CH Wu
doaj   +1 more source

PROTEIN IDENTIFICATION USING SEQUENCE DATABASES

open access: yesScientific Journal of Astana IT University, 2020
The bottom-up proteomics approach (also known as the shotgun approach), based on the digestion of proteins in peptides and their sequencing using tandem mass spectrometry (MS/MS), has become widespread. The identification of peptides from the obtained MS/
Golenko Ye., A. Ismailova, Ye. Rais
doaj  

The Protein Identifier Cross-Referencing (PICR) service: reconciling protein identifiers across multiple source databases

open access: yesBMC Bioinformatics, 2007
Background Each major protein database uses its own conventions when assigning protein identifiers. Resolving the various, potentially unstable, identifiers that refer to identical proteins is a major challenge.
Leinonen Rasko   +8 more
doaj   +1 more source

Proteomics: taking over where genomics leaves off

open access: yesCzech Journal of Genetics and Plant Breeding, 2010
The proteomic studies are simultaneously developed in several directions and significantly influence our notions on the capabilities of biological sciences.
Ritu MAHAJAN, Priyanka GUPTA
doaj   +1 more source

Comparative Assessment of Protein Kinase Inhibitors in Public Databases and in PKIDB

open access: yesMolecules, 2020
Since the first approval of a protein kinase inhibitor (PKI) by the Food and Drug Administration (FDA) in 2001, 55 new PKIs have reached the market, and many inhibitors are currently being evaluated in clinical trials.
Colin Bournez   +6 more
doaj   +1 more source

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