Results 31 to 40 of about 542,743 (309)
Context-specific interactions in literature-curated protein interaction databases
Background Databases of literature-curated protein-protein interactions (PPIs) are often used to interpret high-throughput interactome mapping studies and estimate error rates.
R. Greg Stacey +3 more
doaj +1 more source
How Far Are We from the Completion of the Human Protein Interactome Reconstruction?
After more than fifteen years from the first high-throughput experiments for human protein–protein interaction (PPI) detection, we are still wondering how close the completion of the genome-scale human PPI network reconstruction is, what needs to be ...
Georgios N. Dimitrakopoulos +2 more
doaj +1 more source
Characterization of Protein Complexes and Subcomplexes in Protein-Protein Interaction Databases
The identification and characterization of protein complexes implicated in protein-protein interaction data are crucial to the understanding of the molecular events under normal and abnormal physiological conditions.
Nazar Zaki +2 more
doaj +1 more source
Evaluating deterministic motif significance measures in protein databases
Background Assessing the outcome of motif mining algorithms is an essential task, as the number of reported motifs can be very large. Significance measures play a central role in automatically ranking those motifs, and therefore alleviating the analysis ...
Azevedo Paulo J, Ferreira Pedro
doaj +1 more source
DIP: the Database of Interacting Proteins [PDF]
The Database of Interacting Proteins (DIP; http://dip.doe-mbi.ucla.edu) is a database that documents experimentally determined protein-protein interactions. This database is intended to provide the scientific community with a comprehensive and integrated tool for browsing and efficiently extracting information about protein interactions and interaction
Ioannis Xenarios +5 more
openaire +2 more sources
MultitaskProtDB: a database of multitasking proteins [PDF]
We have compiled MultitaskProtDB, available online at http://wallace.uab.es/multitask, to provide a repository where the many multitasking proteins found in the literature can be stored. Multitasking or moonlighting is the capability of some proteins to execute two or more biological functions. Usually, multitasking proteins are experimentally revealed
Sergio Hernández +7 more
openaire +5 more sources
Optimizing metaproteomics database construction: lessons from a study of the vaginal microbiome
Metaproteomics, a method for untargeted, high-throughput identification of proteins in complex samples, provides functional information about microbial communities and can tie functions to specific taxa.
Elliot M. Lee +8 more
doaj +1 more source
The Protein-DNA Interface database [PDF]
The Protein-DNA Interface database (PDIdb) is a repository containing relevant structural information of Protein-DNA complexes solved by X-ray crystallography and available at the Protein Data Bank. The database includes a simple functional classification of the protein-DNA complexes that consists of three hierarchical levels: Class, Type and Subtype ...
Tomás Norambuena, Francisco Melo 0001
openaire +6 more sources
Human genome resequencing projects provide an unprecedented amount of data about single-nucleotide variations occurring in protein-coding regions and often leading to observable changes in the covalent structure of gene products.
Castrense Savojardo +4 more
doaj +1 more source
The PIR integrated protein databases and data retrieval system
The Protein Information Resource (PIR) provides many databases and tools to support genomic and proteomic research. PIR is a member of UniProt—Universal Protein Resource—the central repository of protein sequence and function, which maintains UniProt ...
H Huang, ZZ Hu, BE Suzek, CH Wu
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