Results 141 to 150 of about 229,295 (345)

Neural topic model with reinforcement learning [PDF]

open access: yes, 2019
In recent years, advances in neural variational inference have achieved many successes in text processing. Examples include neural topic models which are typically built upon variational autoencoder (VAE) with an objective of minimising the error of ...
Pergola, Gabriele   +11 more
core   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

open access: yesFEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Uncovering Flat and Hierarchical Topics by Community Discovery on Word Co-occurrence Network

open access: yesData Science and Engineering
Topic modeling aims to discover latent themes in collections of text documents. It has various applications across fields such as sociology, opinion analysis, and media studies.
Eric Austin   +4 more
doaj   +1 more source

Topic Segmentation of Semi-Structured and Unstructured Conversational Datasets using Language Models

open access: yes, 2023
Breaking down a document or a conversation into multiple contiguous segments based on its semantic structure is an important and challenging problem in NLP, which can assist many downstream tasks.
Srinivasan, Soundararajan   +6 more
core  

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

Systematic Literature Review of Topic Labeling

open access: yesIEEE Access
The rapid growth of textual data on the web has led researchers to develop methods in Natural Language Processing (NLP) to process, understand, and identify topics.
Salma Mekaoui   +3 more
doaj   +1 more source

Applicability of mitotic figure counting by deep learning: a development and pan‐cancer validation study

open access: yesFEBS Open Bio, EarlyView.
In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes   +32 more
wiley   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

Big Data and quality data for fake news and misinformation detection

open access: yesBig Data & Society, 2019
Fake news has become an important topic of research in a variety of disciplines including linguistics and computer science. In this paper, we explain how the problem is approached from the perspective of natural language processing, with the goal of ...
Fatemeh Torabi Asr, Maite Taboada
doaj   +1 more source

Quantitative proteomic analysis reveals different characteristics of bladder cancer cells after exposure to bisphenol A

open access: yesFEBS Open Bio, EarlyView.
Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu   +10 more
wiley   +1 more source

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