Results 51 to 60 of about 509,299 (294)

User–Topic Modeling for Online Community Analysis

open access: yesApplied Sciences, 2020
Analyzing user behavior in online spaces is an important task. This paper is dedicated to analyzing the online community in terms of topics. We present a user–topic model based on the latent Dirichlet allocation (LDA), as an application of topic modeling
Sung-Hwan Kim, Hwan-Gue Cho
doaj   +1 more source

Use of Neural Topic Models in conjunction with Word Embeddings to extract meaningful topics from short texts

open access: yesEAI Endorsed Transactions on Internet of Things, 2022
Unsupervised machine learning is utilized as a part of the process of topic modeling to discover dormant topics hidden within a large number of documents.
Nassera HABBAT   +3 more
doaj   +1 more source

Document Informed Neural Autoregressive Topic Models with Distributional Prior

open access: yes, 2019
We address two challenges in topic models: (1) Context information around words helps in determining their actual meaning, e.g., "networks" used in the contexts "artificial neural networks" vs. "biological neuron networks".
Buettner, Florian   +3 more
core   +1 more source

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

open access: yesMolecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou   +5 more
wiley   +1 more source

Graph Summarization

open access: yes, 2020
The continuous and rapid growth of highly interconnected datasets, which are both voluminous and complex, calls for the development of adequate processing and analytical techniques.
Bonifati, Angela   +2 more
core  

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira   +14 more
wiley   +1 more source

Using Topic Modeling Methods for Short-Text Data: A Comparative Analysis

open access: yesFrontiers in Artificial Intelligence, 2020
With the growth of online social network platforms and applications, large amounts of textual user-generated content are created daily in the form of comments, reviews, and short-text messages.
Rania Albalawi   +2 more
doaj   +1 more source

Text segmentation on multilabel documents: A distant-supervised approach

open access: yes, 2019
Segmenting text into semantically coherent segments is an important task with applications in information retrieval and text summarization. Developing accurate topical segmentation requires the availability of training data with ground truth information ...
Karypis, George, Manchanda, Saurav
core   +1 more source

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

open access: yesMolecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath   +13 more
wiley   +1 more source

Emerging role of ARHGAP29 in melanoma cell phenotype switching

open access: yesMolecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster   +3 more
wiley   +1 more source

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