Results 51 to 60 of about 514,201 (245)

Document Informed Neural Autoregressive Topic Models with Distributional Prior

open access: yes, 2019
We address two challenges in topic models: (1) Context information around words helps in determining their actual meaning, e.g., "networks" used in the contexts "artificial neural networks" vs. "biological neuron networks".
Buettner, Florian   +3 more
core   +1 more source

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

open access: yesMolecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck   +12 more
wiley   +1 more source

User–Topic Modeling for Online Community Analysis

open access: yesApplied Sciences, 2020
Analyzing user behavior in online spaces is an important task. This paper is dedicated to analyzing the online community in terms of topics. We present a user–topic model based on the latent Dirichlet allocation (LDA), as an application of topic modeling
Sung-Hwan Kim, Hwan-Gue Cho
doaj   +1 more source

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

open access: yesMolecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto   +8 more
wiley   +1 more source

Text segmentation on multilabel documents: A distant-supervised approach

open access: yes, 2019
Segmenting text into semantically coherent segments is an important task with applications in information retrieval and text summarization. Developing accurate topical segmentation requires the availability of training data with ground truth information ...
Karypis, George, Manchanda, Saurav
core   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Using Topic Modeling Methods for Short-Text Data: A Comparative Analysis

open access: yesFrontiers in Artificial Intelligence, 2020
With the growth of online social network platforms and applications, large amounts of textual user-generated content are created daily in the form of comments, reviews, and short-text messages.
Rania Albalawi   +2 more
doaj   +1 more source

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

open access: yesMolecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller   +17 more
wiley   +1 more source

Integration of Neural Embeddings and Probabilistic Models in Topic Modeling

open access: yesApplied Artificial Intelligence
Topic modeling, a way to find topics in large volumes of text, has grown with the help of deep learning. This paper presents two novel approaches to topic modeling by integrating embeddings derived from Bert-Topic with the multi-grain clustering topic ...
Pantea Koochemeshkian, Nizar Bouguila
doaj   +1 more source

Graph Summarization

open access: yes, 2020
The continuous and rapid growth of highly interconnected datasets, which are both voluminous and complex, calls for the development of adequate processing and analytical techniques.
Bonifati, Angela   +2 more
core  

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