Results 71 to 80 of about 187,791 (308)

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

The Físchlár-News-Stories system: personalised access to an archive of TV news [PDF]

open access: yes, 2004
The “Físchlár” systems are a family of tools for capturing, analysis, indexing, browsing, searching and summarisation of digital video information. Físchlár-News-Stories, described in this paper, is one of those systems, and provides access to a growing ...
Murphy, Noel   +10 more
core  

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Beyond Established Knowledge Graphs-Recommending Web Datasets for Data Linking [PDF]

open access: yes, 2016
International audienceWith the explosive growth of the Web of Data in terms of size and complexity, identifying suitable datasets to be linked, has become a challenging problem for data publishers.
Konstantin Todorov   +7 more
core   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Topic Modeling Toolkit [PDF]

open access: yes, 2023
The Topic Modeling Toolkit project began with an existing text mining toolkit and aimed to enhance its functionality by incorporating cutting-edge topic modeling techniques.
Pang, Mingkai, Liu, Yulong, Lin, Jiayue
core  

User–Topic Modeling for Online Community Analysis

open access: yesApplied Sciences, 2020
Analyzing user behavior in online spaces is an important task. This paper is dedicated to analyzing the online community in terms of topics. We present a user–topic model based on the latent Dirichlet allocation (LDA), as an application of topic modeling
Sung-Hwan Kim, Hwan-Gue Cho
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Topic Segmentation of Semi-Structured and Unstructured Conversational Datasets using Language Models [PDF]

open access: yes, 2023
Breaking down a document or a conversation into multiple contiguous segments based on its semantic structure is an important and challenging problem in NLP, which can assist many downstream tasks.
Srinivasan, Soundararajan   +6 more
core   +1 more source

Integration of Neural Embeddings and Probabilistic Models in Topic Modeling

open access: yesApplied Artificial Intelligence
Topic modeling, a way to find topics in large volumes of text, has grown with the help of deep learning. This paper presents two novel approaches to topic modeling by integrating embeddings derived from Bert-Topic with the multi-grain clustering topic ...
Pantea Koochemeshkian, Nizar Bouguila
doaj   +1 more source

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