Results 81 to 90 of about 229,295 (345)
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
High performance latent dirichlet allocation for text mining [PDF]
, 2013 This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.Latent Dirichlet Allocation (LDA), a total probability generative model, is a three-tier Bayesian model. LDA computes the latent topic structure of the data
Liu, Zelong
core
Pavement Image Datasets: A New Benchmark Dataset to Classify and Densify Pavement Distresses [PDF]
Transportation Research Record, 2019 Automated pavement distresses detection using road images remains a challenging topic in the computer vision research community. Recent developments in deep learning have led to considerable research activity directed towards improving the efficacy of ...
H. Majidifard +3 more
semanticscholar +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Weakly Supervised Learning of Objects, Attributes and their Associations
, 2014 . When humans describe images they tend to use combinations of nouns and adjectives, corresponding to objects and their associated attributes respectively.
Zhiyuan Shi +11 more
core +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
Investigating the performance of automatic new topic identification across multiple datasets [PDF]
Proceedings of the American Society for Information Science and Technology, 2006 AbstractRecent studies on automatic new topic identification in Web search engine user sessions demonstrated that neural networks are successful in automatic new topic identification. However most of this work applied their new topic identification algorithms on data logs from a single search engine.
Özmutlu, H. Cenk +3 more
openaire +2 more sources
, 2012 The Topic-Focus Database gives information about the ways in which languages give formal expression to information-structural categories such as Topic, Focus and Contrast, and their many subtypes.
CLARIN-NL, TDS Curator
core +1 more source