Results 101 to 110 of about 52,865,053 (238)

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

Uncovering Flat and Hierarchical Topics by Community Discovery on Word Co-occurrence Network

Data Science and Engineering
Topic modeling aims to discover latent themes in collections of text documents. It has various applications across fields such as sociology, opinion analysis, and media studies.
Eric Austin, Shraddha Makwana, Amine Trabelsi, Christine Largeron, Osmar R. Zaïane   +4 more
doaj   +1 more source

Towards Automatic Topical Classification of LOD Datasets.

, 2015
The datasets that are part of the Linking Open Data cloud diagramm (LOD cloud) are classified into the following topical categories: media, government, publications, life sciences, geographic, social networking, user-generated content, and cross-domain. The topical categories were manually assigned to the datasets.
Meusel, Robert, Spahiu, Blerina, Bizer, Christian, Paulheim, Heiko   +3 more
openaire   +3 more sources

Diversity Over Size: On the Effect of Sample and Topic Sizes for Topic-Dependent Argument Mining Datasets

Proceedings of the 2024 Conference on Empirical Methods in Natural Language Processing
The task of Argument Mining, that is extracting and classifying argument components for a specific topic from large document sources, is an inherently difficult task for machine learning models and humans alike, as large Argument Mining datasets are rare and recognition of argument components requires expert knowledge.
Benjamin Schiller, Johannes Daxenberger, Andreas Waldis, Iryna Gurevych   +3 more
openaire   +3 more sources

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

Incorporating topical stance into signed bipartite networks for user retweet prediction.

PLoS ONE
Social networks accelerate information dissemination, and retweet behavior is an important way of user interaction. User retweet prediction analyzes user characteristics to predict retweet behavior and emotional polarity, which can help platforms ...
Lixia Li, Ziqing Chen, Haoran Ye, Yixuan Zhang   +3 more
doaj   +1 more source

Systematic Literature Review of Topic Labeling

IEEE Access
The rapid growth of textual data on the web has led researchers to develop methods in Natural Language Processing (NLP) to process, understand, and identify topics.
Salma Mekaoui, Ilham Chaker, Arsalane Zarghili, Nikola S. Nikolov   +3 more
doaj   +1 more source

Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy

Molecular Oncology, EarlyView.
We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen, Zhi Zhao, Henrik Horndalsveen, Maria Moksnes Bjaanæs, Bjørn Henning Grønberg, Tarje Halvorsen, Tesfaye Madebo, Marianne Aanerud, Jussi Koivunen, Kersti Oselin, Saulius Cicenas, Nina Helbekkmo, Jarkko Ahvonen, Maria Silvoniemi, Tine Norman Alver, Tonje Dalen, Åsa Kristina Öjlert, Saima Jamil Farooqi, Åslaug Helland, Vilde Drageset Haakensen   +19 more
wiley   +1 more source

Human-competitive automatic topic indexing [PDF]

, 2009
Topic indexing is the task of identifying the main topics covered by a document. These are useful for many purposes: as subject headings in libraries, as keywords in academic publications and as tags on the web.
Medelyan, Olena
core  

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

Molecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico, Veronica La Banca, Silvia D'Amico, Stefano Scalera, Sara Nicolai, Angelo Peschiaroli   +5 more
wiley   +1 more source