Results 61 to 70 of about 187,791 (308)

Comparative Evaluation of Hemodiafiltration, Hemoperfusion, and Standard Hemodialysis on Efficacy, Inflammatory Control, Dialysis Adequacy, and Safety in End‐Stage Renal Disease: A Prospective Observational Study

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo   +5 more
wiley   +1 more source

High performance latent dirichlet allocation for text mining [PDF]

open access: yes, 2013
This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.Latent Dirichlet Allocation (LDA), a total probability generative model, is a three-tier Bayesian model. LDA computes the latent topic structure of the data
Liu, Zelong
core  

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Detecting Similar Linked Datasets Using Topic Modelling

open access: yes, 2016
The Web of data is growing continuously with respect to both the size and number of the datasets published. Porting a dataset to five-star Linked Data however requires the publisher of this dataset to link it with the already available linked datasets.
Röder, Michael   +3 more
openaire   +1 more source

Investigating the performance of automatic new topic identification across multiple datasets [PDF]

open access: yesProceedings of the American Society for Information Science and Technology, 2006
AbstractRecent studies on automatic new topic identification in Web search engine user sessions demonstrated that neural networks are successful in automatic new topic identification. However most of this work applied their new topic identification algorithms on data logs from a single search engine.
Özmutlu, H. Cenk   +3 more
openaire   +2 more sources

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Random sampling as a clutter reduction technique to facilitate interactive visualisation of large datasets [PDF]

open access: yes, 2008
Within our physical world lies a digital world populated with an ever increasing number of sizeable data collections. Exploring these large datasets for patterns or trends is a difficult and complex task, especially when users do not always know what ...
Ellis, Geoffrey
core  

Doppler-Shifted Alkali D Line Absorption as Indirect Evidence for Exomoons---Enclosed datasets [PDF]

open access: yes, 2021
This repository holds datasets appearing in the manuscript "Doppler-Shifted Alkali D Line Absorption as Indirect Evidence for Exomoons" Submitted to the Research Topic: Exomoons and Exorings: the Next Frontier in Exoplanets of the journal Frontiers in ...
Carl Schmidt
core   +1 more source

Finding Topic Experts in the Twitter Dataset Using LDA Algorithm

open access: yesInternational Journal of Applied Evolutionary Computation, 2018
In microblogging services like Twitter, the expert judgment problem has gained increasing attention in social media. Twitter is a new type of social media that provides a publicly available way for users to publish 140-character short messages (tweets). However, previous methods cannot be directly applied to twitter experts finding problems.
Ashwini Anandrao Shirolkar   +1 more
openaire   +1 more source

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