Results 61 to 70 of about 649 (161)
Natural products target glycolysis in liver disease [PDF]
, 2023 Mitochondrial dysfunction plays an important role in the occurrence and development of different liver diseases. Oxidative phosphorylation (OXPHOS) dysfunction and production of reactive oxygen species are closely related to mitochondrial dysfunction ...
Liyuan Hao +4 more
core +1 more source
Mitochondrial Dysfunction in Neurodegenerative Diseases
MedComm, Volume 6, Issue 9, September 2025.Overview of mitochondrial dysfunction in neurodegenerative diseases (NDDs). Mitochondrial dysfunction in NDDs involves impaired ATP synthesis, Ca2+ imbalance, oxidative stress, and apoptosis. Assessment methods integrate functional assays, omics, and imaging.
Chongyang Chen +10 more
wiley +1 more source
Alkaloids, Biosynthesis and Their Applications [PDF]
, 2023 Alkaloids are a class of basic, naturally occurring organic compounds that contain at least one nitrogen atom. This group also includes some related compounds with neutral[2] and even weakly acidic properties.[3] Some synthetic compounds of similar ...
Kalani, Rekha +2 more
core +1 more source
New Plant Protection, Volume 2, Issue 3, September 2025.The Tianfu 22 (TF22) variety was identified as resistant to thrips based on field screening carried out over two consecutive years. Metabolomic profiling showed that thrip‐infested TF22 leaves exhibited differentially accumulated metabolites, particularly enriched in phenylpropanoid and secondary metabolite biosynthesis.
Qian Wang +10 more
wiley +1 more source
World Journal of Traditional Chinese Medicine, 2018 Objective: To investigate the network pharmacology of anti-tumor Chinese medicinal formulae and explain the synergistic mechanism of various active ingredients of Chinese medicinal formulae. Methods: We collected the anti-tumor Chinese medicinal formulae
Bao-Yue Zhang +5 more
doaj +1 more source
Food Frontiers, Volume 6, Issue 1, Page 65-85, January 2025.• Overviewed edible TCMs for their hypoglycemic and hypolipidemic potentials • Reviewed screening strategies for bioactive compounds in edible TCMs by UF/LC‐MS • Updated molecular mechanisms of hypoglycemic and hypolipidemic compounds in edible TCMs • Prospected future trends and challenges in more efficient multi‐target based UF/LC‐MS Abstract Edible ...
Xiaowen Hua +8 more
wiley +1 more source
IET Systems Biology, Volume 18, Issue 6, Page 271-284, December 2024.Differential expression of genes between AD patients and the normal population (a) Basic information of GSE5281 dataset. AD patient samples were labelled with green, while control group samples were labelled with purple. (b) Uniform manifold approximation and projection(UMAP) of differentially expressed gene (DEG) in GSE5281. (c) Expression density map
Shaoqiang Wang, Yifan Wang
wiley +1 more source
Autophagy in Multidrug-Resistant Cancers [PDF]
, 2016 Multidrug resistance (MDR) in cancers is the major challenge in cancer therapy, thus the development of sensitizing agents or small molecules with new mechanisms of action to kill the resistant cancers is highly desired.
Law Yuen Kwan, Betty +1 more
core +1 more source
Advanced Science, Volume 11, Issue 19, May 22, 2024.Herein, a chromosome‐level genome assembly of Menispermum dauricum is presented. A novel MdCYP80G10 enzyme is identified to catalyze C2′‐C4a phenol coupling of (S)‐reticuline into sinoacutine, the enantiomer of morphinan compounds, with predictable stereospecificity.
Zhoujie An +20 more
wiley +1 more source