Bioinformatics and Network Pharmacology Identify the Therapeutic Role of Guominkang in Allergic Asthma by Inhibiting PI3K/Akt Signaling. [PDF]
J Inflamm ResHonglei Zhang,1,2,* Haiyun Zhang,1– 3,* Lei Wang,4 Yihang Zhang,1,2 Linhan Hu,1,2 Juntong Liu,1,2 Yumei Zhou,1 Ji Wang1 1National Institute of TCM Body Constitution and Preventive Medicine, Beijing University of Chinese Medicine, Beijing, 100029,
Zhang H +7 more
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Journal of Chemistry, Volume 2024, Issue 1, 2024.Context. Rheumatoid arthritis (RA) is a chronic autoimmune inflammatory disease. It is characterized by persistent joint damage. Traditional Chinese medicine (TCM) has demonstrated notable efficacy in managing RA. Prior investigations have indicated that the ethyl acetate extract of Tetrastigma planicaule (Hook.) Gagnep. (TP) possesses substantial anti‐
Qin Qiu +11 more
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Racemic total synthesis and evaluation of the biological activities of the isoquinoline–benzylisoquinoline alkaloid muraricine [PDF]
, 2020 The first racemic total synthesis of the isoquinoline–benzylisoquinoline alkaloid muraricine is reported herein. Pharmacological characterization identified muraricine as a moderate inhibitor of P‐glycoprotein, a crucial factor of multidrug resistance in
Bartel, Karin +4 more
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Discover ChemistryMetastasis had been a challenging concern for the oncologists in the progressive state of cancer. ubiquitous lysosomal cysteine proteinase, cathepsin L which plays an important role in metastasis in a variety of cancer cells has been taken as a target ...
Poonam R. Inamdar +6 more
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Nelumbo Nucifera (Lotus): A Review on Ethanobotany, Phytochemistry and Pharmacology [PDF]
, 2013 Nelumbo nucifera Gaertn (Nymphaeaceae), a perennial aquatic plant, has been used as a medicinal herb in China and India. It has been recorded in the most famous medicinal book in China for more than 400 years.
Mehta, Nishkruti R. +3 more
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Pharmacological interventions of arrhythmias [PDF]
, 2014 Multiple mechanisms have been implicated in the genesis of early afterdepolarizations (EADs) leading to torsade de pointes (TdP) under long QT syndrome (LQTS).
Parikh, Ashish
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A Computational Systems Pharmacology Approach to Investigate Molecular Mechanisms of Herbal Formula Tian-Ma-Gou-Teng-Yin for Treatment of Alzheimer’s Disease [PDF]
, 2018 Traditional Chinese medicine (TCM) is typically prescribed as formula to treat certain symptoms. A TCM formula contains hundreds of chemical components, which makes it complicated to elucidate the molecular mechanisms of TCM.
Guixia Liu +5 more
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Bioactive Molecules Detection and Identification in Complex Biological Systems through Activity-Based Metabolomics and Proteomics [PDF]
, 2020 The detection and identification of bioactive molecules (e.g. therapeutic small-molecule lead compounds, functional proteins) from complex mixtures is often a critical step in various biochemical and biomedical research fields.
Ma, Hongyan
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식물소재로부터 전립선 비대를 조절하는 생물학적 활성 HX109의 분리와 이에 대한 분자생물학적 분석 [PDF]
, 2020 학위논문(박사)--서울대학교 대학원 :자연과학대학 생명과학부,2020. 2. 이건수.Benign prostatic hyperplasia (BPH) is a common disease in the elderly male population throughout the world. The etiology of BPH has yet to be fully elucidated, but progression of the disease involves various
임선웅
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Isoquinoline alkaloids from Cardiopetalum calophyllum [PDF]
, 1991 Bruneton, J. +4 more
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