Results 111 to 120 of about 13,448,515 (313)

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

open access: yesMolecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad   +2 more
wiley   +1 more source

Longitudinal bi-criteria framework for assessing national healthcare responses to pandemic outbreaks

open access: yesScientific Reports
Pandemics like COVID-19 have illuminated the significant disparities in the performance of national healthcare systems (NHCSs) during rapidly evolving crises. The challenge of comparing NHCS performance has been a difficult topic in the literature.
Adel Guitouni   +5 more
doaj   +1 more source

The impact of the new model of day care on the mental health status and cognitive functions of patients with disabilities treated in day medical care homes in Poland, 2017-2023

open access: yesFrontiers in Psychiatry
IntroductionDay Medical Care Home is a care and treatment institution providing day care services for people with disabilities (mainly older adults), implemented in Poland since 2015. This study aimed to analyze the impact of the new model of day care on
Leszek Warsz   +4 more
doaj   +1 more source

U MEDICAL STUDENTS TO PARTICIPATE IN PRIMARY CARE ACTIVITIES TODAY

open access: yes, 1999
Freshman medical students at the University of Utah will learn how to start their first intravenous (IV) lines this afternoon. The workshop is part of Primary Care Day, an event being held at medical schools across the country to raise awareness of the ...

core  

Bridging the gap: a genetically validated avian chorioallantoic membrane platform for investigation of spontaneous circulating tumor cells

open access: yesMolecular Oncology, EarlyView.
We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth   +17 more
wiley   +1 more source

Adult palliative day-care services : an investigation of the factors influencing access to services using the case of a cancer network in the United Kingdom [PDF]

open access: yes
Background: Literature indicates underutilization of Palliative Care Services in the UK, with possible inequalities of access. These trends in underutilization are seen in Adult-Palliative Day-Care (APDC), a Specialist Palliative Care Service delivered
Greaves, Natalie
core  

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim   +17 more
wiley   +1 more source

FINANCIAL EFFICIENCY OF DAY CARE VERSUS HOSPITALIZATION [PDF]

open access: yesAnnals of the University of Oradea: Economic Science, 2016
Day hospitalization/day care is a service of which can benefit all patients that require thorough investigations to make the diagnosis of a disease, for monitoring chronic diseases, preoperative exploration, microsurgical interventions, postoperative ...
Diana UIVAROSAN   +2 more
doaj  

Medical Day Care Services Waiver Infographic: FY 2019 to FY 2022

open access: yes
The Medical Day Care (MDC) Services Waiver provides health, social, and related support services in a community-based setting to functionally disabled adults aged 16 and older.
The Hilltop Institute
core   +1 more source

Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer

open access: yesMolecular Oncology, EarlyView.
Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba   +5 more
wiley   +1 more source

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