Results 131 to 140 of about 102,789 (325)

Integrative Modeling in the Age of Machine Learning: A Summary of HADDOCK Strategies in CAPRI Rounds 47–55

open access: yesProteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT The HADDOCK team participated in CAPRI rounds 47–55 as server, manual predictor, and scorers. Throughout these CAPRI rounds, we used a plethora of computational strategies to predict the structure of protein complexes. Of the 10 targets comprising 24 interfaces, we achieved acceptable or better models for 3 targets in the human category and 1 ...
Victor Reys   +16 more
wiley   +1 more source

Interplay of Ser273 Phosphorylation and K268 and K293 Acetylation in PPARγ: Implications for PPARγ Activation

open access: yesProteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT Post‐translational modifications (PTMs) play a critical role in regulating the transcriptional activity of PPARγ, a nuclear receptor central to glucose and lipid homeostasis. Among these, lysine acetylation at K268 and K293 and phosphorylation at S273 are particularly relevant to insulin sensitivity.
Caique Camargo Malospirito   +6 more
wiley   +1 more source

Surface Micro‐Discharge Plasma for Multiple Teeth Bleaching: Efficacy, Mechanism and Safety

open access: yesHigh Voltage, EarlyView.
ABSTRACT Hydrogen peroxide (H2O2) is the commonly‐used bleaching chemical in clinical practice, but its excessive concentrations can cause tooth damage. Atmospheric pressure cold plasma is considered a promising new technique for tooth bleaching. Surface micro‐discharge (SMD) devices can generate large‐scale plasma, which holds potential for treating ...
Ruike Chen   +7 more
wiley   +1 more source

Corrosion Failure Analysis of Contactor Type Electrical Connection Components Used in Converter Valve Side Bushings

open access: yesHigh Voltage, EarlyView.
ABSTRACT As a commonly used bushing current‐carrying structure in recent years, contactor‐type electrical connection parts operate in a complex environment of electric, thermal and chemical corrosion for extended periods. With the increase of ultra‐high voltage (UHV) transmission capacity, its operating environment faces more stringent challenges, and ...
Qingyu Wang   +9 more
wiley   +1 more source

Degradation of organic compounds and production of activated species in Dielectric Barrier Discharges and Glidarc reactors

open access: yes, 2007
Major sterilization mechanisms are related to atoms and radicals, charged parti-cles, excited molecules, ozone, and UV radiation. The ROS (Reactive Oxygen Species) are well known as evildoers. These species are easily created in ambient air and water and
Aubry, Olivier   +2 more
core  

Allergic Rhinitis and Its Impact on Asthma (ARIA)‐EAACI Guidelines—2024–2025 Revision: Part II—Guidelines on Oral and Ocular Treatments

open access: yesAllergy, EarlyView.
ABSTRACT Background Oral and ocular medications are frequently used in the treatment of allergic rhinitis (AR). As part of the update of the Allergic Rhinitis and its Impact on Asthma (ARIA)‐EAACI guidelines, this manuscript presents the ARIA‐EAACI 2024–2025 recommendations for oral and ocular treatments.
Rafael José Vieira   +230 more
wiley   +1 more source

Magnetic Resonance Imaging Evaluation of Functional Differences Between In Vivo Human Kidneys and Discarded Human Kidneys During Ex Vivo Normothermic Machine Perfusion

open access: yesArtificial Organs, EarlyView.
Comparative MRI of in vivo kidneys and ex vivo donor kidneys during NMP revealed marked physiological differences and limited correspondence with conventional perfusion or injury metrics. These distinct ex vivo MRI signatures emphasize the need to consider parameters beyond conventional in vivo functional markers when assessing organ viability during ...
Tim L. Hamelink   +12 more
wiley   +1 more source

Profil Lipid pada Fase Akut Demam Berdarah Dengue

open access: yesJurnal Kedokteran dan Kesehatan, 2016
Lipid dan lipoprotein bisa menjadi penentu derajat manifestasi infeksi dengue pada fase awal. Telah dilakukan beberapa penelitian mengenai faktor tersebut, namun hasilnya masih kontroversi.Penelitian ini bertujuan untuk mengetahui hubungan profil lipid ...
Sari Mulia   +3 more
doaj  

ROWVA: A Structure‐Based Metric for Predicting the Pathogenicity of Protein Variants Using Alphafold2

open access: yesCancer Science, EarlyView.
This study investigates whether several AF2‐derived scores can predict functional scores and pathogenicity labels, and suggests that the root mean square deviation between the wild‐type and variant structures predicted by AlphaFold2 (ROWVA) may be the most effective predictor. This approach may also be applicable to other multimeric proteins.
Taiki Furutani   +7 more
wiley   +1 more source

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