Results 111 to 120 of about 27,085 (244)
Proteins: Structure, Function, and Bioinformatics, Volume 94, Issue 9, Page 1597-1609, September 2026.ABSTRACT Post‐translational modifications (PTMs) play a critical role in regulating the transcriptional activity of PPARγ, a nuclear receptor central to glucose and lipid homeostasis. Among these, lysine acetylation at K268 and K293 and phosphorylation at S273 are particularly relevant to insulin sensitivity.
Caique Camargo Malospirito +6 more
wiley +1 more source
Course of Portal Hypertension and Its Prognostic Impact After Liver Transplantation
United European Gastroenterology Journal, Volume 14, Issue 7, September 2026.ABSTRACT Background While portal hypertension (PH) typically resolves after liver transplantation (LT), persistence of PH may affect post‐transplant outcomes. We assessed the evolution of PH after LT and its impact on adverse outcomes. Methods We recorded clinical, laboratory, and imaging parameters of LT recipients between 2016 and 2022 in Vienna and ...
Nina Dominik +20 more
wiley +1 more source
Comprehensive Reviews in Food Science and Food Safety, Volume 25, Issue 5, September 2026.ABSTRACT Pulse flours, such as those from peas, beans, and chickpeas, are highly valued for their nutritional density, making them essential for meeting the rising global demand for plant‐based and gluten‐free foods. Despite these nutritional advantages, industrial use is limited by specific sensorial, nutritional, and technological constraints ...
Federico Drudi +2 more
wiley +1 more source
Economic Costs and Benefits of the Digital OurRelationship Program for Distressed Couples
Family Process, Volume 65, Issue 3, September 2026.ABSTRACT Relationship distress is a prevalent issue with significant economic and societal consequences, including increased mental and physical health problems, decreased workplace productivity, and increased absences. Although couple therapy has been shown to improve relationship and individual well‐being, its high costs limit accessibility.
Brian D. Doss +4 more
wiley +1 more source
Advanced Science, Volume 13, Issue 45, 13 August 2026.The aptamer WHY‐3E identifies PrPC as a CRC driver. Stabilized by USP18, endocytosed PrPC forms a LYN/STAT3 complex, upregulating MSN transcription to promote metastasis. Crucially, WHY‐3E sensitively detects PrPC‐positive circulating exosomes, establishing a robust theoretical foundation for non‐invasive clinical diagnostics.
Chunlin Wang +23 more
wiley +1 more source
All‐Flex Plasma Patch for In Vivo Delivery of Reactive Species
Advanced Science, Volume 13, Issue 45, 13 August 2026.A fully flexible plasma patch enables stable, conformal treatment on complex biological surfaces and enhances transdermal delivery of reactive species. This platform achieves significant tumor suppression in vivo and reveals coordinated regulation of calcium signaling, metabolism, and programmed cell death, providing a promising strategy for safe and ...
Luxiang Zhao +8 more
wiley +1 more source
, 2014 Dielectric barrier discharge based electrostatic precipitators powered by a nanosecond pulsed high voltage is investigated experimentally in this paper. The first goal is to characterize the behavior of the discharge in wire-to-square tube configuration.
Aba'a Ndong, Arthur Claude +2 more
openaire +1 more source
A Tale of Two Mechanisms: The p53 Modulator COTI‐2 Is a Zn Metallochaperone
Drug Development Research, Volume 87, Issue 5, August 2026.ABSTRACT Mutations in, or misregulation of, Tp53 are found in approximately 50% of all cancers. p53 functions by ensuring that cells with irretrievably damaged DNA undergo apoptosis. Tp53 mutations often induce conformational changes that inhibit activity; however, small‐molecule chaperones could theoretically restore conformation and activity. COTI‐2,
İrem Şimşek +16 more
wiley +1 more source
The DBD-α4 helix of EWSR1::FLI1 is required for GGAA microsatellite binding that underlies genome regulation in Ewing sarcoma. [PDF]
ElifeBayanjargal A +7 more
europepmc +1 more source