Results 31 to 40 of about 63,754 (306)
Design Method of Double-Boost DC/DC Converter with High Voltage Gain for Electric Vehicles
World Electric Vehicle Journal, 2020 Direct current to direct current (DC/DC) converters are required to have higher voltage gains in some applications for electric vehicles, high-voltage level charging systems and fuel cell electric vehicles. Therefore, it is greatly important to carry out
Zhengxin Liu, Jiuyu Du, Boyang Yu
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Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Soft-Switching Full-Bridge DC-DC Converter with Energy Recovery Capacitor Snubber
Energies, 2023 This paper describes a high-frequency soft-switching dc-dc converter with a simple energy recovery capacitor snubber on the secondary side. The presented dc-dc full-bridge converter with the energy recovery snubber removes the main drawbacks of the ...
Marek Pastor +3 more
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Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
Design of an AC/DC Converter with using Supercapacitors as Energy Storage
RMUTL Engineering Journal, 2016 This paper presents a design of a high power factor AC/DC converter with using supercapacitors as energy storage.The proposed system consists of a cuk topology based AC/DC power converter and a bidirectional DC/DC converter which is connected between the
พิสิทธิ วิสุทธิเมธีกร +1 more
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IEEE Access, 2023 DC-connected ultra-fast chargers consist of isolated DC/DC converter modules to provide the required charging profile. This paper proposes a charging module that interfaces with a fixed voltage DC-bus and covers a wide variety of electric vehicles (EVs ...
Ahmed Elezab +3 more
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Molecular Oncology, EarlyView.The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
IEEE AccessElectric vehicle transportation is a constantly advancing technology. In electric vehicles, battery charging is a critical necessity. The demand for DC/DC bidirectional converters in electric vehicle electrical systems is significantly higher than that ...
Nalluri Ramya Sri, M. Praveen Kumar
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Design and Analysis of Feedback Control for DC-DC Buck Converter [PDF]
, 2021 Sajad Ahmad Tali +2 more
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The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity
Molecular Oncology, EarlyView.Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli +7 more
wiley +1 more source