Results 41 to 50 of about 1,605 (264)

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Performance investigation of two-level reduced-switch D-STATCOM in grid-tied solar-PV array with stepped P&O MPPT algorithm and modified SRF strategy

Journal of King Saud University: Engineering Sciences, 2023
In this paper, a Two-Level, Three-Phase, Reduced-Switch (2L3PRS) Voltage Source Converter (VSC) based Distribution Static Synchronous Compensator (DSTATCOM) integrated with a grid-tied solar photo-voltaic (PV) array has been discussed, and its ...
Meenakshi Rastogi, Aijaz Ahmad, Abdul Hamid Bhat   +2 more
doaj   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Voltage Balancing Strategy for V-Clamp Multilevel Converter Under High Modulation Index and High Power Factor Condition

IEEE Access, 2021
Featured with the simple structure, V-clamp multilevel converter (VMC) shows good prospect in the high-voltage and high-power applications. But VMC is endangered by the deviation of dc-link capacitors voltage, especially under the high modulation index ...
Yao Xue, Chenchen Wang, Jiawei Guo, Trillion Q. Zheng, Xiaofeng Yang   +4 more
doaj   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source

Control of AC/DC Modular Multilevel Converter

Elektronika ir Elektrotechnika, 2018
In recent years, a special attention is paid to grid connected multilevel converters. These converters have specific use in industry in a high power, medium-voltage and high-voltage applications. This paper presents new control algorithm for single-phase
Vojtech Blahnik, Tomas Kosan, Zdenek Peroutka, Jakub Talla   +3 more
doaj   +1 more source

Comprehensive modeling and formulation of split DC link capacitors balancing problem in Three-Phase Three-Level bidirectional AC/DC converters operating with arbitrary power factor

Alexandria Engineering Journal, 2023
Three-phase three-level AC/DC and DC/AC converters have demonstrated several advantages over their classical two-level counterparts such as better efficiency, enhanced total harmonic distortion, lower dv/dt and lesser overall chip area.
Yan Vule, Yarden Siton, Alon Kuperman
doaj   +1 more source

Heterotropic regulation and negative homotropic cooperativity

FEBS Open Bio, EarlyView.
We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea, Francesco Angelucci, Federica Arnesano, Gianmarco Pascarella, Patrizio Di Micco, Andrea Bellelli   +5 more
wiley   +1 more source

Triple Line-Voltage Cascaded VIENNA Converter Applied as the Medium-Voltage AC Drive

Energies, 2018
A novel rectifier based on a triple line-voltage cascaded VIENNA converter (LVC-VC) was proposed. Compared to the conventional cascaded H-bridge converters, the switch voltage stress is lower, and the numbers of switches and dc capacitors are fewer under
Jia Zou, Cong Wang, Hong Cheng, Jinqi Liu   +3 more
doaj   +1 more source