Results 41 to 50 of about 2,997,503 (289)

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

A Family of 5-Level Boost-Active Neutral-Point-Clamped (5L-BANPC) Inverters with Full DC-Link Voltage Utilization Designed Using Half-Bridges

Energies
Conventional 5-level active neutral-point-clamped (5L-ANPC) topology and state-of-the-art 5-level hybrid active neutral-point-clamped (5L-HANPC) topology are popular for inverter applications. However, their dc-link voltage utilization is limited to only
Sze Sing Lee
doaj   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Quantum Mode Series Resonant Converter Utilized as Active Voltage Regulator of a Split DC Bus Capacitor

IEEE Access, 2023
Certain modern power electronics systems require active regulation of the split DC bus capacitor voltages. The series resonant converter is suitable to be utilized as an active voltage regulator, due to its ability to operate with soft switching, and ...
Igor Lopusina, Yann E. Bouvier, Petar J. Grbovic   +2 more
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Four-Level Single-Stage Single-Source Boost-Inverter

IEEE Access
This paper presents a novel concept of a DC-AC converter that ensures AC voltage modulation on four levels using a single branch and achieves voltage boosting.
Robert Stala, Szymon Folmer, Zbigniew Waradzyn, Adam Penczek, Stanislaw Pirog, Aleksander Skala, Andrzej Mondzik, Krishna Kumar Gupta, Pallavee Bhatnagar, Sanjay K. Jain   +9 more
doaj   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

FEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança, Eline L. Jansen, Jorine M. Eeftens   +2 more
wiley   +1 more source

Performance investigation of two-level reduced-switch D-STATCOM in grid-tied solar-PV array with stepped P&O MPPT algorithm and modified SRF strategy

Journal of King Saud University: Engineering Sciences, 2023
In this paper, a Two-Level, Three-Phase, Reduced-Switch (2L3PRS) Voltage Source Converter (VSC) based Distribution Static Synchronous Compensator (DSTATCOM) integrated with a grid-tied solar photo-voltaic (PV) array has been discussed, and its ...
Meenakshi Rastogi, Aijaz Ahmad, Abdul Hamid Bhat   +2 more
doaj   +1 more source

Voltage Balancing of the DC-Link Capacitors in Three-Level T-Type Multiphase Inverters

IEEE Transactions on Power Electronics, 2022
This paper illustrates an algorithm to balance the voltages across the DC-link capacitors of a three-level multiphase inverter feeding a star-connected load with an odd number of phases. The proposed strategy keeps the DC-link capacitors balanced in any operating condition and minimizes the low-frequency voltage oscillations, even during open-phase ...
Vancini L., Mengoni M., Rizzoli G., Zarri L., Tani A.   +4 more
openaire   +2 more sources

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source