Results 41 to 50 of about 135,907 (264)

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

Modular Multilevel Converter DC Fault Protection [PDF]

open access: yesIEEE Transactions on Power Delivery, 2018
High voltage direct current grids will require the development of dc protections that provide fast fault isolation and minimize the disturbance caused to the existing ac power networks. This paper investigates how the dc fault recovery performance of a half-bridge modular multilevel converter (HB-MMC) is impacted by different dc protection design ...
Cwikowski, O   +6 more
openaire   +4 more sources

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Study on the Vectoring Potential of Halyomorpha halys for Pantoea stewartii subsp. stewartii, the Pathogen Causing Stewart’s Disease in Maize

open access: yesAgriculture
Pantoea stewartii subsp. stewartii (Pss) is a Gram-negative bacterium first documented in North America, and is the causal agent of Stewart’s disease in maize (Zea mays), especially in sweet corn. First identified in North America, it is primarily spread
Francesca Costantini   +6 more
doaj   +1 more source

Punicalagin Content and Antifungal Activity of Different Pomegranate (Punica ganatum L.) Genotypes

open access: yesHorticulturae, 2019
This study investigated the antifungal activity of a number of pomegranate genotypes. Since the main compound of pomegranate extract is punicalagin, an important substance involved in antifungal and antimicrobial activity, we analyzed the contents of ...
Domenico Rongai   +5 more
doaj   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

open access: yesMolecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park   +6 more
wiley   +1 more source

Research on Strategy of DC Micro-grid Control and Protection

open access: yes南方能源建设, 2020
[Introduction] The control and protection technology of DC microgrid plays an important role in ensuring the reliable and safe operation of DC microgrid. The paper aims to solve the key technologies in the design of DC micro-grid.
ZHOU Yu   +4 more
doaj   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

open access: yesMolecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla   +4 more
wiley   +1 more source

DC Bus Overcurrent Protection Scheme in Metro DC Traction Power Supply System Based on Boolean Logic Calculation

open access: yesChengshi guidao jiaotong yanjiu
[Objective] To enable accurate determination of DC (direct current) bus overcurrent protection in metro DC traction power supply system and enhance the selectivity of fault tripping in the system, the research on a suitable DC bus overcurrent protection ...
LIU Yuxing   +5 more
doaj   +1 more source

New-Generation Sequencing Technology in Diagnosis of Fungal Plant Pathogens: A Dream Comes True?

open access: yesJournal of Fungi, 2022
The fast and continued progress of high-throughput sequencing (HTS) and the drastic reduction of its costs have boosted new and unpredictable developments in the field of plant pathology.
Maria Aragona   +7 more
doaj   +1 more source

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